Mineral and heavy metal concentration of nutritionally and therapeutically valued wild plants: Insights into health effects

Abstract

Background and Aims: The purpose of the study was to determine the concentrations of minerals and heavy metals in nutri- tive and therapeutically valued wild plants Allium orientale Boiss., Eremurus spectabilis M. Bieb., Anchusa officinalis L. and Arum elongatum Steven.
Methods: The presence and quantity of 23 minerals and heavy metals were analyzed by inductively coupled plasma mass spectrometry (ICP-MS).
Results: The most common minerals were P, Mg, K, Ca, Fe and Al. Moderately abundant elements were Na, Sr, Zn, Cu, Mn, B and Ni. Toxic heavy metals such as Sn, Li, Co, Se, Sb, Hg, Cd, As and Pb were present at very low concentrations or were not detected. A. officinalis was observed to be rich in K (7496.435 mg/kg) and Ca (2947.378 mg/kg). On the other hand, Fe concentrations were high in A. orientale (1022.068 mg/kg) and A. elongatum (699.932 mg/kg). The Mg concentration in A. orientale (731.012 mg/kg) was almost double that in the other three plants. Al was found in high concentrations in A. orien- tale (889.368 mg/kg) and A. elongatum (651.570 mg/kg). Cr concentration of A. orientale, A. officinalis and A. elongatum exceeded both EPA limits and standard concentrations in plants.
Conclusion: The study reveals the elemental profile, heavy metal content and possible effects on human health of four wild plants that are frequently used in alternative medicine and nutrition. Most of the elements are not at detrimental levels. Addi- tionally, the results can be useful for the food and pharmaceutical industries and to guide nutritional and comparative studies.

Keywords

• Edible wild plant
• Mineral
• Heavy Metal
• Nutrition
• Medicinal plant

References

1. Aberoumand, A., & Deokule, S. S. (2009). Determination of ele- ments profile of some wild edible plants. Food Analytical Methods, 2(2), 116–119. https://doi.org/10.1007/s12161-008-9038-z
2. Apori, S. O., Atiah, K., Hanyabui, E., & Byalebeka, J. (2020). Mor- inga Oleifera seeds as a low-cost biosorbent for removing heavy metals from wastewater. STED Journal, 2(1), 45–52. https://doi. org/10.7251/STED2002045O
3. Barthwal, J., Nair, S., & Kakkar, P. (2008). Heavy metal accumula- tion in medicinal plants collected from environmentally differ- ent sites. Biomedical and Environmental Sciences, 21(4), 319–324. https://doi.org/10.1016/S0895-3988(08)60049-5
4. Bedassa, M., Abebaw, A., & Desalegn, T. (2017). Assessment of se- lected heavy metals in onion bulb and onion leaf (Allium cepa L.), in selected areas of central rift valley of Oromia region Ethiopia. Journal of Horticulture, 4(4), 217. https://doi.org/10.4172/2376-0354.1000217
5. Bhat, R., Kiran, K., Arun, A. B., & Karim, A. A. (2010). Determination of mineral composition and heavy metal content of some nu- traceutically valued plant products. Food Analytical Methods, 3(3), 181–187. https://doi.org/10.1007/s12161-009-9107-y
6. Ceylan, O., & Alıc, H. (2015). Antibiofilm, antioxidant, antimuta- genic activities and phenolic compounds of Allium orientale BOISS. Brazilian Archives of Biology and Technology, 58(6), 935–943. https://doi.org/10.1590/S1516-89132015060309
7. Chizzola, R., & Lukas, B. (2006). Variability of the cadmium content in Hypericum species collected in Eastern Austria. Water, Air, and Soil Pollution, 170(1–4), 331–343. https://doi.org/10.1007/s11270- 005-9004-y
8. Dixit, R., Wasiullah, Malaviya, D., Pandiyan, K., Singh, U., Sahu, A.,… Paul, D. (2015). Bioremediation of heavy metals from soil and aquatic environment: An overview of principles and criteria of fundamental processes. Sustainability, 7(2), 2189–2212. https:// doi.org/10.3390/su7022189

9. Jaishankar, M., Tseten, T., Anbalagan, N., Mathew, B. B., & Beer- egowda, K. N. (2014). Toxicity, mechanism and health effects of some heavy metals. Interdisciplinary Toxicology, 7(2), 60–72. https://doi.org/10.2478/intox-2014-0009
10. Jakovljević, D., Vasić, S., Stanković, M., Topuzović, M., & Čomić, L. (2016). The content of secondary metabolites and in vitro biologi- cal activity of Anchusa officinalis L. (Boraginaceae). Indian Journal of Traditional Knowledge, 15(4), 587–593.
11. Jaradat, N., & Abualhasan, M. (2016). Comparison of phytocon- stituents, total phenol contents and free radical scavenging capacities between four Arum species from Jerusalem and Bethlehem. Pharmaceutical Sciences, 22(2), 120–125. https://doi. org/10.15171/PS.2016.19
12. Kabata-Pendias, A., & Pendias, H. (2001). Trace elements in soils and plants (3rd ed). Boca Raton, Fla: CRC Press.
13. Karahan, F., Ozyigit, I. I., Saracoglu, I. A., Yalcin, I. E., Ozyigit, A. H., & Ilcim, A. (2020). Heavy metal levels and mineral nutrient status in different parts of various medicinal plants collected from Eastern Mediterranean region of Turkey. Biological Trace Element Research, 197(1), 316–329. https://doi.org/10.1007/s12011-019-01974-2
14. Kardaş, C. (2019). Muş’ta yabani bitkilerin halk hekimliğinde kullanılması [Usage of savage plants in the folk medicine in Muş]. Lokman Hekim Journal, 9(1), 85–96. https://doi.org/10.31020/mutftd.468848
15. Kim, H. L., Streltzer, J., & Goebert, D. (1999). St. John’s Wort for depression: A meta-analysis of well-defined clinical trials. Journal of Nervous and Mental Disease, 187(9), 532–538. https://doi. org/10.1097/00005053-199909000-00002
16. Long, S., & Romani, A. M. (2015). Role of cellular magnesium in hu- man diseases. Austin Journal of Nutrition & Food Sciences, 2(10), 19.
17. Maharia, R. S., Dutta, R. K., Acharya, R., & Reddy, A. V. R. (2010). Heavy metal bioaccumulation in selected medicinal plants col- lected from Khetri copper mines and comparison with those collected from fertile soil in Haridwar, India. Journal of Environ- mental Science and Health, Part B, 45(2), 174–181. https://doi. org/10.1080/03601230903472249
18. Malluche, H. (2002). Aluminum and bone disease in chronic renal failure. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 17 Suppl 2, 21–24. https://doi.org/10.1093/ndt/17. suppl_2.21
19. Masarovičová, E., Katarina, K., Kummerová, M., & Kmentova, E. (2004). The effect of cadmium on root growth and respiration rate of two medicinal plant species. Biologia, 59(13), 211–214.
20. Molloy, D. W., Standish, T. I., Nieboer, E., Turnbull, J. D., Smith, S. D., & Dubois, S. (2007). Effects of acute exposure to Alu- minum on cognition in humans. Journal of Toxicology and Environmental Health, Part A, 70(23), 2011–2019. https://doi. org/10.1080/15287390701551142
21. Muhammad, S., Shah, M. T., & Khan, S. (2011). Heavy metal con- centrations in soil and wild plants growing around Pb–Zn sulfide terrain in the Kohistan region, northern Pakistan. Mi- crochemical Journal, 99(1), 67–75. https://doi.org/10.1016/j.mi- croc.2011.03.012
22. Neenu, S., & Karthika, K. S. (2019). Aluminium toxicity in soil and plants. Harit Dhara, 2(1), 15–19.
23. Nik Abdul Ghani, N. R., Jami, M., & Alam, M. (2021). The role of nano- adsorbents and nanocomposite adsorbents in the removal of heavy metals from wastewater: A review and prospect. Pollution, 7(1), 153–179. https://doi.org/10.22059/poll.2020.307069.859
24. Okcu, M., Tozlu, E., Kumlay, A. M., & Pehluvan, M. (2009). Ağır met- allerin bitkiler üzerine etkileri [The effects of heavy metals on plants]. Alinteri Journal of Agriculture Science, 17(2), 14–26.
25. Ozyigit, I. I., Yalcin, B., Turan, S., Saracoglu, I. A., Karadeniz, S., Yal- cin, I. E., & Demir, G. (2018). Investigation of heavy metal level and mineral nutrient status in widely used medicinal plants’ leaves in Turkey: Insights into health implications. Biological Trace Element Research, 182(2), 387–406. https://doi.org/10.1007/s12011-017-1070-7
26. Roy, C. N., & Enns, C. A. (2000). Iron homeostasis: New tales from the crypt. Blood, 96(13), 4020–4027.
27. Santos, D., Batoreu, C., Mateus, L., Marreilha dos Santos, A. P., & Aschner, M. (2014). Manganese in human parenteral nutrition: Considerations for toxicity and biomonitoring. NeuroToxicology, 43, 36–45. https://doi.org/10.1016/j.neuro.2013.10.003
28. Sarma, H., Deka, S., Deka, H., & Saikia, R. R. (2012). Accumulation of heavy metals in selected medicinal plants. In D. M. Whita- cre (Ed.), Reviews of Environmental Contamination and Toxicol- ogy (pp. 63–86). New York, NY: Springer New York. https://doi. org/10.1007/978-1-4614-0668-6_4
29. Soetan, K. O., Olaiya, C. O., & Oyewole, O. E. (2010). The importance of mineral elements for humans, domestic animals and plants: A review. African Journal of Food Science, 4(45), 200–222.
30. Tosun, M., Ercisli, S., Ozer, H., Turan, M., Polat, T., Ozturk, E., … Kilic- gun, H. (2012). Chemical composition and antioxidant activity of Foxtail Lily (Eremurus spectabilis). Acta Scientiarum Polonorum Hortorum Cultus, 11(3), 145–153.
31. Verotta, L. (2003). Hypericum perforatum, a source of neuroac- tive lead structures. Current Topics in Medicinal Chemistry, 3(2), 187–201. https://doi.org/10.2174/1568026033392589
32. Wang, Q. R., Cui, Y. S., Liu, X. M., Dong, Y. T., & Christie, P. (2003). Soil contamination and plant uptake of heavy metals at polluted sites in China. Journal of Environmental Science and Health, Part A, 38(5), 823–838. https://doi.org/10.1081/ESE-120018594