Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye

İlker Kurt; Esen Gül Koçak; Selma Sezer Demirel; Miray Akbaş; Begüm Sanat Dayı; Mine Sezgin; Bedia Samancı; Betül Baykan; Haşmet Ayhan Hanağası; B. Sönmez Uydeş Dogan; Nihan Carcak Yılmaz

doi:10.26650/IstanbulJPharm.2026.1814416

Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye

Abstract

Background and Aims: The prevalence and characteristics of drug-related problems (DRPs) and factors associated with the occurrence of DRPs in inpatients in the neurology department in Türkiye remain unknown. This study aimed to determine the characteristics of DRPs and to identify drug-drug interactions (DDIs) in the neurology department of a tertiary university hospital in Türkiye.

Methods: This prospective study with clinical pharmacist (CP) intervention was conducted at the Department of Neurology, Istanbul University Istanbul Faculty of Medicine Hospital, between December 2023 and June 2024 by clinical pharmacy residents (CPRs). The characteristics of DRPs were categorised using the Pharmaceutical Care Network Europe (PCNE) DRP classification tool V9.1, and DDIs were identified using Micromedex® drug interaction software.

Results: A total of 106 DRPs were detected in 63 inpatients, an average of 1.68 DRPs per patient. Using the PCNE classification system, treatment safety (P2) was identified as the most common type of DRP (69; 65.09%), whereas drug selection (C1) was the primary cause (94; 83.93%). CPRs provided a total of 120 interventions, and most interventions occurred at the prescriber level (I1) (107; 89.17%), and all were accepted. A total of 205 DDIs were detected (59/63;93.65%), most of which were classified as major (136;66.34%).

Conclusions: This study demonstrates that DRPs can occur at any stage of the prescribing process and are common among inpatients in the neurology department in Türkiye. These findings may encourage further research on the roles of CPs in neurology departments using controlled study designs.

Keywords

References

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Details

Primary Language

English

Subjects

Clinical Pharmacy and Pharmacy Practice

Journal Section

Research Article

Authors

İlker Kurt
0000-0002-4932-4183
Türkiye

Esen Gül Koçak
0009-0000-5714-031X
Türkiye

Selma Sezer Demirel
0000-0001-5056-3790
Türkiye

Miray Akbaş
0000-0001-7662-1223
Türkiye

Begüm Sanat Dayı
0000-0001-9210-7152
Türkiye

Mine Sezgin
0000-0001-6525-0658
Türkiye

Bedia Samancı
0000-0003-0667-2329
Türkiye

Betül Baykan
0000-0002-3360-659X
Türkiye

Haşmet Ayhan Hanağası
0000-0002-4624-4428
Türkiye

B. Sönmez Uydeş Dogan
0000-0002-6729-8150
Türkiye

Nihan Carcak Yılmaz ^*
0000-0001-6254-4319
Türkiye

Publication Date

May 21, 2026

Submission Date

October 31, 2025

Acceptance Date

February 9, 2026

Published in Issue

Year 2026 Volume: 56 Number: 1

DOI

https://doi.org/10.26650/IstanbulJPharm.2026.1814416

IZ

https://izlik.org/JA68BH94CU

Cite

RIS / Bibtex

APA

Kurt, İ., Koçak, E. G., Sezer Demirel, S., Akbaş, M., Dayı, B. S., Sezgin, M., Samancı, B., Baykan, B., Hanağası, H. A., Uydeş Dogan, B. S., & Carcak Yılmaz, N. (2026). Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye. İstanbul Journal of Pharmacy, 56(1), 27-35. https://doi.org/10.26650/IstanbulJPharm.2026.1814416

AMA

1.Kurt İ, Koçak EG, Sezer Demirel S, et al. Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye. iujp. 2026;56(1):27-35. doi:10.26650/IstanbulJPharm.2026.1814416

Chicago

Kurt, İlker, Esen Gül Koçak, Selma Sezer Demirel, et al. 2026. “Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye”. İstanbul Journal of Pharmacy 56 (1): 27-35. https://doi.org/10.26650/IstanbulJPharm.2026.1814416.

EndNote

Kurt İ, Koçak EG, Sezer Demirel S, Akbaş M, Dayı BS, Sezgin M, Samancı B, Baykan B, Hanağası HA, Uydeş Dogan BS, Carcak Yılmaz N (May 1, 2026) Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye. İstanbul Journal of Pharmacy 56 1 27–35.

IEEE

[1]İ. Kurt et al., “Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye”, iujp, vol. 56, no. 1, pp. 27–35, May 2026, doi: 10.26650/IstanbulJPharm.2026.1814416.

ISNAD

Kurt, İlker - Koçak, Esen Gül - Sezer Demirel, Selma - Akbaş, Miray - Dayı, Begüm Sanat - Sezgin, Mine - Samancı, Bedia et al. “Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye”. İstanbul Journal of Pharmacy 56/1 (May 1, 2026): 27-35. https://doi.org/10.26650/IstanbulJPharm.2026.1814416.

JAMA

1.Kurt İ, Koçak EG, Sezer Demirel S, Akbaş M, Dayı BS, Sezgin M, Samancı B, Baykan B, Hanağası HA, Uydeş Dogan BS, Carcak Yılmaz N. Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye. iujp. 2026;56:27–35.

MLA

Kurt, İlker, et al. “Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye”. İstanbul Journal of Pharmacy, vol. 56, no. 1, May 2026, pp. 27-35, doi:10.26650/IstanbulJPharm.2026.1814416.

Vancouver

1.İlker Kurt, Esen Gül Koçak, Selma Sezer Demirel, Miray Akbaş, Begüm Sanat Dayı, Mine Sezgin, Bedia Samancı, Betül Baykan, Haşmet Ayhan Hanağası, B. Sönmez Uydeş Dogan, Nihan Carcak Yılmaz. Evaluation of Drug-Related Problems in Inpatients at the Neurology Department of Tertiary University Hospital in Türkiye. iujp. 2026 May 1;56(1):27-35. doi:10.26650/IstanbulJPharm.2026.1814416