Yıl 2022,
, 357 - 361, 30.12.2022
Gamze Çamlık
Yıldız Özsoy
,
İsmail Tuncer Değim
Kaynakça
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A smarter, tactical approach for combating Covid-19
Yıl 2022,
, 357 - 361, 30.12.2022
Gamze Çamlık
Yıldız Özsoy
,
İsmail Tuncer Değim
Öz
As human beings, we communicate with each other just like other creatures. In the same way we need to communicate, COV- ID-19 has to communicate with other viruses. Following the latest Pandemic, combating COVID-19 has become a major need today. Several theories are being formulated and tested for the efficient prevention and treatment of the virus. Vaccination is the ultimate solution but access to the vaccine and getting vaccinated is limited. The purpose of this review paper is to present a new approach. This approach is based on the Quorum sensing of viruses like bacteria. Bacteria use this for communication and it has recently been proven for viruses too. It can be used as a new way or strategy to stop viral communication, therefore restricting the viral spread will possibly help people around the world or reduce the disease’s side effects. This new tactic in- volves the use of functionalized Quantum dots nanoparticles, and when they are coupled with carbon atoms and put to use in different delivery forms, these will be useful for maximum efficacy. The use of carbon quantum dots can be useful to minimize certain possible toxic effects. This may be greatly enhanced by doping boron atoms to the structure to trigger their synergistic effects. We suggest here that the inhaler form of this proposed drug delivery system should simultaneously provide a fairly high efficiency and a less toxic solution.
Kaynakça
- Arumugam, S. S., & Malaichamy, I. (2015). Comprehensive mul- tispectroscopic analysis on the interaction and corona forma- tion of human serum albumin with gold/silver alloy nanopar- ticles. Journal of Physical Chemistry B, 119, 9461-9476. https://doi. org/10.1021/acs.jpcb.5b00436
- Arumugam, S. S., & Malaichamy, I. (2015). Comprehensive mul- tispectroscopic analysis on the interaction and corona forma- tion of human serum albumin with gold/silver alloy nanopar- ticles. Journal of Physical Chemistry B, 119, 9461-9476. https://doi. org/10.1021/acs.jpcb.5b00436
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- Bi, J., Li, Y., Wang, H., Song, Y., Cong, S., Yu, C., Zhu, B. W., & Tan, M. (2017). Presence and formation mechanism of foodborne carbo- naceous nanostructures from roasted pike eel (Muraenesox ci- nereus). Journal of Agricultural and Food Chemistry, 66, 2862-2869. https://doi.org/10.1021/acs.jafc.7b02303
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- Carnes, E. C., Lopez, D. M., Donegan, N. P., Cheung, A., Gresham, H., & Timmins, G.S. (2010). Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria. Nature Chemical Biol- ogy, 6(1), 41–45. https://doi.org/10.1038/nCHeMBIO.264
- Chen, D., Ganesh, S., Wang, W., & Amiji, M. M. (2017). Plasma pro- tein adsorption and biological identity of systemically adminis- tered nanoparticles. Nanomedicine, 12, 2113-2135. https://doi. org/10.2217/nnm-2017-0178
- Chen, D., Ganesh, S., Wang, W., & Amiji, M. M. (2017). Plasma pro- tein adsorption and biological identity of systemically adminis- tered nanoparticles. Nanomedicine, 12, 2113-2135. https://doi. org/10.2217/nnm-2017-0178
- Chen, D., Ganesh, S., Wang, W., & Amiji, M. M. (2019). Role of sur- face chemistry on serum protein corona-mediated cellular de- livery and gene silencing with lipid nanoparticles. Nanoscale, 11, 8760-8775. https://doi.org/10.1039/C8NR09855G
- Chen, D., Ganesh, S., Wang, W., & Amiji, M. M. (2019). Role of sur- face chemistry on serum protein corona-mediated cellular de- livery and gene silencing with lipid nanoparticles. Nanoscale, 11, 8760-8775. https://doi.org/10.1039/C8NR09855G
- Degim, I.T. & Kadioglu, D. (2013). Cheap, Suitable, Predictable and Manageable Nanoparticles for Drug Delivery: Quantum Dots, Current Drug Delivery, 10(1), 32-38.
- Degim, I.T. & Kadioglu, D. (2013). Cheap, Suitable, Predictable and Manageable Nanoparticles for Drug Delivery: Quantum Dots, Current Drug Delivery, 10(1), 32-38.
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- Dietrich, L. E., Price-Whelan, A., Petersen, A., Whiteley, M., & New- man, D. K. (2006). The phenazine pyocyanin is a terminal signal- ing factor in the quorum sensing network of Pseudomonas ae- ruginosa. Molecular Microbiology, 61(5), 1308–1321. https://doi. org/10.1111/j.1365-2958.2006.05306.x
- Dolgin, E. (2019). The secret social lives of viruses. Na- ture, 570(7761), 290-292.
- Dolgin, E. (2019). The secret social lives of viruses. Na- ture, 570(7761), 290-292.
- Duncan, T. V. (2011). The communication challenges presented by nanofoods. Nature Nanotechnology, 6, 683-688.
- Duncan, T. V. (2011). The communication challenges presented by nanofoods. Nature Nanotechnology, 6, 683-688.
- Erez, Z., Steinberger-Levy, I., Shamir, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S., Amita, G. & Sorek, R. (2017). Nature, 541, 488–493. https://doi.org/10.1038/ nature21049
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- Girma, W.M., Fahmi, M.Z., Permadi, A., Abate, M.A. & Chang, J.Y (2017). Synthetic strategies and biomedical applications of I-III-VI ternary quantum dots. Journal of Materials Chemistry, 5(31), 6193- 6216. https://doi.org/10.1039/C7TB01156C
- Girma, W.M., Fahmi, M.Z., Permadi, A., Abate, M.A. & Chang, J.Y (2017). Synthetic strategies and biomedical applications of I-III-VI ternary quantum dots. Journal of Materials Chemistry, 5(31), 6193- 6216. https://doi.org/10.1039/C7TB01156C
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