The correlation between botanical source and the biologically active compounds of propolis

Yıl 2019, Cilt: 49 Sayı: 2, 81 - 87, 01.08.2019

Ömür Gençay Çelemli , Mehmet Atakay Kadriye Sorkun

Öz

DOI: 10.26650/IstanbulJPharm.2019.435408

In this research, five propolis samples
collected from Turkey were investigated to observe the correlation between
botanical sources and chemical contents of the samples and in this way
emphasize the influence of botanical sources of propolis on its chemical
characterization. As a first step, to determine the botanical sources of the
samples, microscopic analysis was performed. According to the microscopic
analysis results; two samples that were collected from Rize (P1 and P2), were
characterized as most probably being chesnut propolis; while one sample
collected from Tekirdağ (P3) was evaluated as being a mixed type, in the other
Tekirdağ sample (P4), the pollens belonging to the taxa of the Brassicaceae
family were found as dominant. The sample collected from Sivas (P5); was also
recognized as  mixed type. The second
step of the research was the chemical analyses of the propolis samples.
According to the results; the balsamic contents of the propolis samples ranged
between 59.97 and 83.31%, total phenolic contents were ranged between
27.56±0.05 and 171.93±0.28 mgGAE/g. The minimum flavone and flavonol content of
0.28±0.01% was found in the P1 sample described as chesnut propolis and
colected from Rize. The maximum value 5.1±0.07% was found in the P4 sample as
was total phenolic content. Flavanones and Dihydroflavonols contents varied
between 6.58±0.009-12.94±0.007%. According to the GC-MS results the
investigated samples contained compounds belonging to the various groups. With
regard to the Excel correllation,  the
balsamic content showed a negative correlation with total phenolic content,
flavone and flavonol content, flavanones and dihydroflavonols content.

Cite this article as: Gençay Çelemli Ö,
Atakay M, Sorkun K (2019). The correlation between botanical source and the
biologically active compounds of propolis. Istanbul J Pharm 49 (2): 81-87.

Anahtar Kelimeler

Propolis, chestnut, microscopic, total phenolic, UV-Vis, GC-MS

Kaynakça

• Ahn MR, Kumazawa S, Usui Y, Nakamura M, Matsuka M, Zhu F, Nakayama T (2007). Antioxidant activity and constituents of propolis collected in various areas of China. Food Chem 101: 1383-1392. Barth OM (1998). Pollen analysis of Brazilian propolis. Grana 37: 97-101. Bonvehi JS, Coll FV, Jorda RE (1994). The composition, active components and bacteriostatic activity of propolis in dietetics. J American Oil Chemists’ Society 71: 529-532. Burdock GA (1998). Review of the Biologşcal Properties and Toxicity of Nee Propolis (propolis). Food Chem Toxicol 36: 347-363. Chen CN, Weng MS, Wu CL, Lin JK (2004). Comparison of Radical Scavenging Activity, Cytotoxic Effects and Apoptosis Induction in Human Melanoma Cells by Taiwanese Propolis From Different Sources. Evid Based Complement Alternat Med 1: 175-185. Choi YM, Noh DO, Cho SY, Suh HJ, K.m KM, Kim JM (2006). Antioxidant and antimicrobial activities of propolis from several regions of Korea. Food Sci Technol 39: 756-761. Choi SJ, Shimomura K, Kumazawa S, Ahn MR (2013). Antioxidant properties and phenolic composition of propolis from diverse geographic regions in Korea. Food Sci Technol Res 19: 211-222. Cottica SM, Sawaya ACHHF, Eberlin MN, Franco SLF, Zeoula LM, Visentainer JV (2011). Antioxidant activity and Composition of propolis obtained by different method of extraction. J Braz Chem Soc 22: 929-935. Cunha IBS, Sawaya ACHF, Caetano FB, Shimizu MT, Marcucci MC, Drezza FT, Povia GS, Carvalho PO (2004). Factors that influence the yield and composition of Brazilian Propolis Extracts. J Braz Chem Soc 15: 964-970. Çelemli ÖG, Sorkun K (2012). The plant choices of Honey Bees to Collect Propolis İn Tekirdağ-Turkey. Hacettepe J Biol Chem 40: 45-51. Daleprane JB, Abdalla D S (2013). Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions. Evid Based Complement Alternat Med doi: 10.1155/2013/175135. E. Gençay, Ö (2004). Identification of Botanical Origin and Chemical Composition of Propolis From Kemaliye-Erzincan Region. Master Thesis. Gençay Ö, Salih B (2008). GC-MS Analysis of Propolis Samples From Different Regions of Turkey, Four Different Regions of Brazil and One From Japan. Mellifera 9: 19-28. Ghisalberti EL (1979). Propolis: a review. Bee World 60: 59-84. Gómez-Caravaca AM, Gómez-Romero M, Arráez-Román D, Segura-Carretero A, Fernández-Gutiérrez A (2006). Advances in the analysis of phenolic compounds in products derived from bees. J Pharm Biomed Anal 41: 1220-1234. Gülçin İ, Bursal E, Şehitoğlu MH, Bilsel M, Gören AC (2010). Polyphenol contents and antioxidant activity of lyophilized extract of propolis from Erzurum, Turkey. Food Chem Toxicol 48: 2227-2238. Jun X (2006). Comparison of Antioxidant activity of Ethanolic Extracts of Propolis Obtained By Different Extraction Methods. Can J Chem Eng 84: 447-451. Kalogeropoulos N, Konteles SJ, TRoullidou E, Mourtzinos I, Karathanos V (2009). Chemical composition, antioxidant activity and antimicrobial properties of propolis extracts from Greece and Cyprus. Food Chem 116: 452-461. Kumazawa S, Hasmasaka T, Nakayama T (2004). Antioxidant activity of propolis of various geographic origins. Food Chem 84: 329-339. Maciejewicz W, Daniewski M, Markowski W (2001). GC-MS Identification of the Flavonoid Aglycones Isolated from Propolis. Chromatographia 53: 343-346. Marcucci MC (1995). Propolis : chemical composition, biological properties and therapeutic activity. Apidologie 26: 83-99. Mohammadzadeh S, Sharriatpanahi M, Hamedi M, Amanzadeh Y, Ebrahimi SES, Ostad SN (2007). Antioxidant power of Iranian propolis extract. Food Chem 103: 729-733. Moreira L, Dias LG, Pereira JA, Estevinho L (2008). Antioxidant properties, total phenols and pollen analysis of propolis samples from Portugal. Food Chem Toxicol 46: 3482-3485. Popova M., Bankova V Butovska D, Petkov V, Nikolova-Damyanova B, Sabatini AG, Marcazzan GL, Bogdanov S (2004). Validated Methods for the Quantification of Biologically Active Constituents of Poplar-type Propolis. Phytochemical Analysis 15: 235-240. Popova M, Silici S, Kaftanoğlu O, Bankova V (2005). Antibacterial activity of Turkish propolis and its qualitative and quantitative chemical composition. Phytomedicine 12: 221-228. Popova MP, Bankova VS, Bogdanov S, Tsvetkova I, Naydenski C, Marcazzan GL, Sabatini AG (2007). Chemical characteristics of poplar type propolis of different geographic origin. Apidologie 38: 306-311. Sarıkaya AO, Ulusoy E, Öztğrk N, Tunçel M, Kolaylı S (2009). Antioxidant Activity and Phenolic Acid Constituents of Chesnut (Castanea Sativa Mill.) Honey and Propolis. J Food Biochem 33: 470-481. Silva JFM, Souza MC, Matta SR, Andrade MR, Vidal FVN (2006). Correlation analysis between phenolic levels of Brazilian propolis extracts and their antimicrobial and antioxidant activities. Food Chemistry 99: 431-435. Trusheva B., Trunkova D, Bankova V (2007). Different extraction methods of biologically act ive components from propolis: a preliminary study. Chemisrty Central Journal 1: 13. Valencia D, Alday E, Zepeda RR, Escobar A, Ruiz JC, Reyes M, Estrada M, Conteras E, Hermandez J, Velazquez C (2012). Seasonal effect on chemical composition and biological activities of Sonoran propolis. Food Chemistry 131: 645-651. Warakomska Z, Maciejewicz (1992). Microscopic analysis of propolis from Polish regions. Apidologie 23: 277-283. Woisky RC, Salatino A (1998). Analysis of propolis: some parameters and procedures for chemical quality control. J Apicult Res 37: 99-105. Yaghoubi SMJ, Ghorbani GR, Soleimanian ZS, Satari R (2007). Antimicrobial activity of Iranian propolis and its chemical composition. DARU 15: 1.