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Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system

Yıl 2010, Sayı: 3, 1 - 6, 01.11.2010

Ali Asghar Tehranı Navid Hosseini Mansoub Mina Maghsoudlo Seyede Lale Zabıhı Hakimeh Rasoolıan

Öz

Phenobarbital, a barbiturate, is used as an asleep aid and in the treatment of certain types of seizure and anxiety. The placenta offers no significant barrier to the passage of barbiturate to the foetus. This study was carried out to investigate the pathological affect of Phenobarbital on the nervous system and subsequent retardation of muscle of biceps brachii, triceps brachii, soleus, tibialis cranialis, gastroneumius. Prenatal exposure of rats to Phenobarbital was accomplished in utero by giving their mothers food to which was added 3g Phenobarbital per kg feed.The microscopic pathology of brain revealed various degrees of degenerative and necrotic changes in different parts of brain. Big vacuoles, edema and hemorrhage were also noted. There were significant differences between the absolute weights and muscle mass indices of control and prenatally Phenobarbitalexposed groups. It is concluded that prenatal administration of Phenobarbital had detrimental effects on rat nervous and muscular system

Anahtar Kelimeler

Androgen phenobarbital necrosis prenatal rat

Yıl 2010, Sayı: 3, 1 - 6, 01.11.2010

Ali Asghar Tehranı Navid Hosseini Mansoub Mina Maghsoudlo Seyede Lale Zabıhı Hakimeh Rasoolıan

Öz

Toplam 0 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA22TV34SB
Bölüm Araştırma Makalesi
Yazarlar

Ali Asghar Tehranı Bu kişi benim

Navid Hosseini Mansoub Bu kişi benim

Mina Maghsoudlo Bu kişi benim

Seyede Lale Zabıhı Bu kişi benim

Hakimeh Rasoolıan Bu kişi benim

Yayımlanma Tarihi 1 Kasım 2010
Yayımlandığı Sayı Yıl 2010 Sayı: 3

Kaynak Göster

APA Tehranı, A. A., Mansoub, N. H., Maghsoudlo, M., Zabıhı, S. L., vd. (2010). Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system. Journal of Applied Biological Sciences(3), 1-6.
AMA Tehranı AA, Mansoub NH, Maghsoudlo M, Zabıhı SL, Rasoolıan H. Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system. J.appl.biol.sci. Kasım 2010;(3):1-6.
Chicago Tehranı, Ali Asghar, Navid Hosseini Mansoub, Mina Maghsoudlo, Seyede Lale Zabıhı, ve Hakimeh Rasoolıan. “Pathological Investigation on Pre-Natal Use of Phenobarbital in the Rat Nervous and Muscular System”. Journal of Applied Biological Sciences, sy. 3 (Kasım 2010): 1-6.
EndNote Tehranı AA, Mansoub NH, Maghsoudlo M, Zabıhı SL, Rasoolıan H (01 Kasım 2010) Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system. Journal of Applied Biological Sciences 3 1–6.
IEEE A. A. Tehranı, N. H. Mansoub, M. Maghsoudlo, S. L. Zabıhı, ve H. Rasoolıan, “Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system”, J.appl.biol.sci., sy. 3, ss. 1–6, Kasım 2010.
ISNAD Tehranı, Ali Asghar vd. “Pathological Investigation on Pre-Natal Use of Phenobarbital in the Rat Nervous and Muscular System”. Journal of Applied Biological Sciences 3 (Kasım 2010), 1-6.
JAMA Tehranı AA, Mansoub NH, Maghsoudlo M, Zabıhı SL, Rasoolıan H. Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system. J.appl.biol.sci. 2010;:1–6.
MLA Tehranı, Ali Asghar vd. “Pathological Investigation on Pre-Natal Use of Phenobarbital in the Rat Nervous and Muscular System”. Journal of Applied Biological Sciences, sy. 3, 2010, ss. 1-6.
Vancouver Tehranı AA, Mansoub NH, Maghsoudlo M, Zabıhı SL, Rasoolıan H. Pathological investigation on pre-natal use of Phenobarbital in the Rat Nervous and Muscular system. J.appl.biol.sci. 2010(3):1-6.