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Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males

Yıl 2012, Cilt: 6 Sayı: 2, 19 - 22, 01.07.2012

Osamah Batiha Mohammed A. Al-ghazo Ahmed M. Elbetieha Saied A. Jaradat

Öz

Infertility is a serious problem that affects between 10%-15% of couples all over the world in which half of these cases are attributed to males. Deletions in the azoospermia factor (AZF) of the Y chromosome have been investigated and shown to be associated with azoospermia and severe oligozoospermia in many populations. However, the percentages of microdeletions were somehow variable. The purpose of this study was to investigate the association between microdeletions in the AZF region of the Y chromosome and infertility among male Jordanians.A total of 65 oligoozospermic and non-obstructive azoospermic infertile men (Study group) and 20 fertile men (control group) were investigated for microdeletions in the AZF using multiplex PCR. We found one out of 65 (1.5%) had Y microdeletions. Microdeletions were detected in the AZFb and AZFc regions. The percentage of Y chromosome microdeletions in Jordanian infertile males is considered low compared to that from other countries. We also report a molecular genetic characterization of a sex-reversed 46,XX male, a very rare genetic abnormality in humans

Anahtar Kelimeler

Y chromosome microdeletions male infertility

Yıl 2012, Cilt: 6 Sayı: 2, 19 - 22, 01.07.2012

Osamah Batiha Mohammed A. Al-ghazo Ahmed M. Elbetieha Saied A. Jaradat

Öz

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Ayrıntılar

Diğer ID JA48AJ52ZH
Bölüm Araştırma Makalesi
Yazarlar

Osamah Batiha Bu kişi benim

Mohammed A. Al-ghazo Bu kişi benim

Ahmed M. Elbetieha Bu kişi benim

Saied A. Jaradat Bu kişi benim

Yayımlanma Tarihi 1 Temmuz 2012
Yayımlandığı Sayı Yıl 2012 Cilt: 6 Sayı: 2

Kaynak Göster

APA Batiha, O., Al-ghazo, M. A., Elbetieha, A. M., Jaradat, S. A. (2012). Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males. Journal of Applied Biological Sciences, 6(2), 19-22.
AMA Batiha O, Al-ghazo MA, Elbetieha AM, Jaradat SA. Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males. J.appl.biol.sci. Temmuz 2012;6(2):19-22.
Chicago Batiha, Osamah, Mohammed A. Al-ghazo, Ahmed M. Elbetieha, ve Saied A. Jaradat. “Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males”. Journal of Applied Biological Sciences 6, sy. 2 (Temmuz 2012): 19-22.
EndNote Batiha O, Al-ghazo MA, Elbetieha AM, Jaradat SA (01 Temmuz 2012) Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males. Journal of Applied Biological Sciences 6 2 19–22.
IEEE O. Batiha, M. A. Al-ghazo, A. M. Elbetieha, ve S. A. Jaradat, “Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males”, J.appl.biol.sci., c. 6, sy. 2, ss. 19–22, 2012.
ISNAD Batiha, Osamah vd. “Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males”. Journal of Applied Biological Sciences 6/2 (Temmuz 2012), 19-22.
JAMA Batiha O, Al-ghazo MA, Elbetieha AM, Jaradat SA. Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males. J.appl.biol.sci. 2012;6:19–22.
MLA Batiha, Osamah vd. “Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males”. Journal of Applied Biological Sciences, c. 6, sy. 2, 2012, ss. 19-22.
Vancouver Batiha O, Al-ghazo MA, Elbetieha AM, Jaradat SA. Screening for Deletions in the AZF Region of Y Chromosome in Infertile Jordanian Males. J.appl.biol.sci. 2012;6(2):19-22.