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Toward Domain-Specific AI: The Potential of Small Language Models in Radiology
Abstract
As this submission is a letter to the editor, an abstract is not included.
Keywords
Supporting Institution
None.
Ethical Statement
This submission is a letter to the editor and does not involve human or animal subjects; therefore, ethical approval is not required.
Thanks
The authors have no acknowledgments to declare..
References
- 1- Alkalbani AM, Alrawahi AS, Salah A, et al. A systematic review of large language models in medical specialties: applications, challenges and future directions. Inform. 2025;16(6):489. doi:10.3390/info16060489
- 2- Bhayana R. Chatbots and large language models in radiology: a practical primer for clinical and research applications. Radiology. 2024;310(1):e232756. doi:10.1148/radiol.232756
- 3- Nakaura T, Ito R, Ueda D, et al. The impact of large language models on radiology: a guide for radiologists on the latest innovations in AI. Jpn J Radiol. 2024;42:685-696. doi:10.1007/s11604-024-01552-0
- 4- Salbas A, Buyuktoka RE. Performance of large language models in recognizing brain MRI sequences: a comparative analysis of ChatGPT-4o, Claude 4 Opus, and Gemini 2.5 Pro. Diagnostics (Basel). 2025;15(15):1919. doi:10.3390/diagnostics15151919
- 5- Salbas A, Yogurtcu M. Performance of large language models on radiology residency in-training examination questions. Acad Radiol. Published online November 11, 2025. doi:10.1016/j.acra.2025.10.043
- 6- Akinci D'Antonoli T, Stanzione A, Bluethgen C, et al. Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions. Diagn Interv Radiol. 2024;30(2):80-90. doi:10.4274/dir.2023.232417
- 7- Ranjit M, Srivastav S, Ganu T. RadPhi-3: small language models for radiology. arXiv preprint arXiv:2411.13604. Published online 2024. doi:10.48550/arXiv.2411.13604
Details
Primary Language
English
Subjects
Radiology and Organ Imaging
Journal Section
Letter to Editor
Publication Date
December 30, 2025
Submission Date
November 25, 2025
Acceptance Date
December 7, 2025
Published in Issue
Year 2025 Volume: 5 Number: 3