Ovarian Cysts in Guinea Pigs and Hormonal Treatment as an Option

Year 2026, Volume: 1, 1 - 6, 29.12.2025

Üzeyir Yiğit Uysal , Serhat Özsoy

Abstract

Ovarian cysts are a common health concern in female guinea pigs, notably affecting those aged 2 to 4 years. They are generally seen bilaterally. Interestingly, prevalence doesn’t significantly correlate with reproductive history, but cyst size tends to increase with age. There are two primary cyst types: serous rete cysts and follicular cysts, each necessitating specific diagnostic and treatment considerations. Serous rete cysts are nonhormonal and typically asymptomatic, becoming problematic only if they grow excessively. In contrast, hormonally active follicular cysts exhibit clinical signs such as bilateral symmetrical nonprurutic alopecia, clitoral hypertrophy, alopecia, and reduced fertility. Diagnosis involves various methods, including hematology, hormone testing, radiography, ultrasonography, and histopathology. Treatment options encompass surgery, cyst aspiration, and hormonal therapy. Cyst aspiration is a temporary solution. Hormonal treatments, particularly utilizing GnRH, hCG, and GnRH agonists, have proven effective for follicular cysts, although with variable outcomes requiring case-specific evaluation. Surgical intervention may be considered in cases where hormonal treatment is ineffective for serous rete cysts. In conclusion, the nuanced management of ovarian cysts in guinea pigs demands an understanding of cyst types, diagnostic tools, and tailored treatment strategies.

Keywords

guinea pig , hormone , ovarium cysts , follicular cysts , treatment

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