Upper Respiratory Tract Infections and Rhino-Pharyngeal Clearance in Children: Myths and Clinical Evidence for a Pictorial Essay
Abstract
Keywords
- upper respiratory tract infections
- rhino-pharyngeal clearance
- tympanometry
- treatment outcomes
- future research
Ethical Statement
References
- Jackson S, Mathews KH, Pulanić D, Falconer R, Rudan I, Campbell H, Nair H. Risk factors for severe acute lower respiratory infections in children–a systematic review and meta-analysis. Croat Med J 2013;54(2):110-121.
- Alexandrino AS, Santos R, Melo C, Bastos JM. Risk factors for respiratory infections among children attending day care centres. Family Prac 2016;33(2):161-166.
- Chirico G, Quartarone G, Mallefet P. Nasal congestion in infants and children: a Literature review on efficacy and safety of non-pharmacological treatments. Minerva Pediatr 2014;66 (6):549-557.
- Alexandrino AS, Santos R, Melo C, Bastos JM, Postiaux G. Caregivers’ education vs rhinopharyngeal clearance in children with upper respiratory infections: impact on children’s health outcomes. Eur J Pediatr 2017;176(10):1375-1383.
- Albasser MM, Sanchez E, Fernandes MB, Patel N, Novak P, Hagen M. Safety and Performance of Narhinel 0.9% Sodium Chloride Monodose and Otrisal 0.74% Sodium Chloride Monodose Nasal Saline Solutions and Nasal Aspirators in Real-World Settings: Postmarket Clinical Follow-up Study Results. Current Therapeutic Res 2023;99:100725.
- Cruz M, Roteia C, Marques-Ferreira A, Barros R, Sevivas H, Gomes T, Bandeira AS. Nasal Irrigation With Saline Solution for Pediatric Acute Upper Respiratory Infections: A Systematic Review. Cureus 2024;16(12):e75464.
- Khales P, Razizadeh MH, Ghorbani S, Moattari A, Saadati H, Tavakoli A. Prevalence of respiratory viruses in children with respiratory tract infections during the COVID-19 pandemic era: a systematic review and meta-analysis. BMC Pulmonary Medicine 2025;25(1):135.
- Li S, Sun XC, Wu ZF, et al. Nasal irrigation for the prevention and treatment of upper respiratory tract infection by SARS-CoV-2: a narrative review. The Journal of Infection in Developing Countries 2024;18(9.1):S81-S91.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Review
Authors
Ana Silva Alexandrino
0000-0001-8146-6950
Portugal
David Tome
0000-0002-1824-1019
Portugal
Paulo Abreu
0000-0001-7535-2711
Portugal
Şule Çekiç
*
0000-0001-8174-800X
Türkiye
Patrícia Carvalho
0009-0009-9450-5432
Portugal
Publication Date
September 30, 2026
Submission Date
January 11, 2025
Acceptance Date
September 7, 2026
Published in Issue
Year 2026 Volume: 10 Number: 3