Peripheral Blood Cell Changes And Outcomes After Partial Splenic Embolization For Hypersplenism İn Cirrhotic Patients

Year 2025, Volume: 9 Issue: 1, 182 - 187, 31.01.2025

Süleyman Dolu , Göksel Bengi , Nilay Danış , Müjde Soytürk , İlker Büyüktorun , Hüseyin Döngelli , Mücahit Özbilgin , Aytaç Gülcü , Orkun Sarıoğlu , İsmail Nafi Özdamar , Ömer Selahattin Topalak

https://doi.org/10.30621/jbachs.1561027

Abstract

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Peripheral Blood Cell Changes And Outcomes After Partial Splenic Embolization For Hypersplenism İn Cirrhotic Patients

Abstract

Background and Purpose: Partial splenic embolization is a common treatment for hypersplenism in patients with cirrhosis. In this investigation, we evaluated the effectiveness and safety of partial splenic embolization in patients with cirrhosis.
Methods: We retrospectively investigated 17 patients with hypersplenism secondary to cirrhosis who underwent partial splenic embolization. Following partial splenic embolization, peripheral blood cell counts were measured at regular intervals over a period of twelve months.Post-procedural complications were recorded.
Results: This study included 17 individuals, with a mean age of 54.5 ± 10 years. Hemoglobin, platelet, neutrophil, lymphocyte, and white blood cell counts showed statistically significant increases.when compared to the pre-procedure levels at each time point (pre-procedure vs. 1st day p<0.001; pre-procedure vs. 1st week p<0.001; pre-procedure vs. 1st month p<0.001; pre-procedure vs. 6th month p<0.001; pre-procedure vs. 1st year p<0.001). The most common complication was post-embolization syndrome (88.2%), which was managed with conservative treatment. One patient died of esophageal variceal bleeding.
Conclusion: Partial splenic embolization improves long-term hematological parameters, with manageable side effects

Keywords

Partial splenic embolization , cirrhosis , hypersplenism

Ethical Statement

We state that the author has read and approved submission of the manuscript, and the manuscript has not been published and is not being considered for publication elsewhere in whole or part of it in any language. This study was completed in accordance with the tenets of the Declaration of Helsinki. There is no conflict of interest.

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