j clin exp invest Journal of Clinical and Experimental Investigations 1309-8578 1309-6621 Aydın ECE 10.5799/ahinjs.01.2011.04.0095 Vitamin B12 deficiency and depression Vitamin B12 deficiency and depression Milanlıoğlu Aysel 12 01 2011 2 4 02 27 2015 Copyright © 2010, Journal of Clinical and Experimental Investigations 2010 Journal of Clinical and Experimental Investigations

Vitamin B12 deficiency may cause psychiatric manifestations preceding the hematological and neurological symptoms. Despite a variety of symptoms, data on the role of vitamin B12 deficiency in depression are sparse. We report a case with B12 deficiency that is diagnosed with psychotic depression and treated successively with vitamin B12 replacement instead of using conventional therapy. Future investigations should focus on the role of vitamin B12 status in depression and other neuropsychiatric disorders. J Clin Exp Invest 2011; 2 (4): 455-456

B12 vitamin eksikliği, hematolojik ve nörolojik semptomlardan önce psikiyatrik tablolara neden olabilmektedir. Pek çok semptoma rağmen B12 vitamin eksikliğinin depresyondaki rolü ile ilgili veriler nadirdir. Biz, psikotik depresyon tanısı konulan, konvansiyonel tedavi yerine B12 replasmanı ile başarılı bir şekilde tedavi edilen B12 vitamin eksikliği olan bir vakayı sunuyoruz. Gelecekteki araştırmalar, B12 vitamininin depresyon ve diğer nöropsikiyatrik bozukluklar üzerindeki etkilerine odaklanmalıdır.

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