Surrenal Yetersizlik

Yıl 2008, Cilt: 8 Sayı: 3, 145 - 151, 01.07.2008

Hülya Günöz

Öz

Adrenal yetersizlik göreceli olarak çocukluk ve ergenlik döneminde nadirdir, primer ve sekonder, konjenital ve edinsel olarak gruplandırılabilir. Primer adrenal yetersizlik nedenleri arasında konjenital adrenal hiperplazi, otoimmün adrenal yetersizlik, Wolman, triple A, Zellweger gibi bazı sendromlar sayılabilir. Sekonder adrenal yetersizliğe ise glukokortikoid tedavinin kesilmesi, adrenal süpresyon durumunda stres ortaya çıkması ve primer ACTH eksikliğine bağlı ortaya çıkabilir. Glukokortikoid ve mineralokortikoid yerine koyma tedavisi gereklidir. Adrenal kriz adrenal yetersizliği olan çocuklarda hastalıklar sırasında yetersiz glukokortikoid tedaviye bağlı olarak ortaya çıkabilir. Adrenal yetersizliğin erken tanınması ve tedavi edilmesi önemlidir. Adrenal krizin önlenmesi için sağlık görevlilerine ve ailelere öneriler yapılmalıdır.

Anahtar Kelimeler

Surrenal yetersizlik, çocuk, glukokortikoid

Adrenal Insufficiency

Öz

Adrenal insufficiency is relatively rare in childhood and adolescence, and may be categorized as primary or secondary and congenital or acquired. Primary adrenal insufficiency causes include congenital adrenal hyperplasia, autoimmune adrenal insufficiency, adrenoleucodystrophy, syndromes Wolman, triple A, Zellweger, etc. . Secondary adrenal insufficiency may occur due to discontinuation of glucocorticoid therapy or stress on suppressive doses, deficiency primary ACTH. Glucocorticoid and mineralocorticoid replacement therapy are necessary. If unrecognized, adrenal insufficiency may present with life-threatening cardiovascular collapse. Adrenal crisis continues to occur in children with adrenal insufficiency during acute disease because of failure to increase glucocorticoid dose. Early recognition and treatment of adrenal insufficiency are most important. Suggestions for prevention of adrenal crisis in patients at risk are provided for families and health care professionals.

Anahtar Kelimeler

Adrenal insufficiency, childhood, glucocorticoid

Kaynakça

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