DNA METİLASYONUNA NEDEN OLAN MİKOTOKSİNLERİN ELEKTROANALİTİK YÖNTEMLERLE ANALİZİ

Öz

Amaç: DNA metilasyonunu etkileyen mikotoksinlerin analizi toksikolojide gıda güvenliği açısından oldukça önemlidir. Mikotoksin maruziyetinin kontrolü ile anlaşılması, gelişmiş gıda işleme teknikleri ve uygun depolama uygulamalarıyla birleştirildiğinde, gıda güvenliğinin artırılmasına olanak verir. Sonuç ve Tartışma: Bu derleme, çeşitli yaygın mikotoksinlerin (aflatoksin B1, okratoksin A, vb.) neden olduğu DNA metilasyonundaki değişiklikleri ve bunların tespiti için kullanılan elektroanalitik yöntemleri özetlemektedir.

Anahtar Kelimeler

• DNA metilasyonu
• elektroanalitik yöntemler
• mikotoksin

ANALYSIS OF MYCOTOXINS CAUSING DNA METHYLATION BY ELECTROANALYTICAL METHODS

Öz

Objective: The analysis of mycotoxins affecting DNA methylation is of great importance in toxicology for food safety. Control and understanding of mycotoxin exposure, combined with improved food processing techniques and appropriate storage practices, allows for increased food safety. Result and Discussion: This review summarizes the changes in DNA methylation caused by several common mycotoxins (aflatoxin B1, ochratoxin A, etc.) and the electroanalytical methods used for their detection.

Anahtar Kelimeler

• DNA methylation
• electroanalytical method
• mycotoxin

Kaynakça

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