AN OVERVIEW OF THE CHEMICAL COMPOSITION, BIOLOGICAL ACTIVITIES AND TRADITIONAL USES OF GENUS ALKANNA TAUSCH
Yıl 2025,
Cilt: 49 Sayı: 2, 519 - 538, 19.05.2025
Sadi Yusufbeyoğlu
,
Ayşe Baldemir Kılıç
Öz
Objective: This study summarizes some scientific studies conducted on the chemical contents and biological activities of the Alkanna genus, which is thought to be medically important and has various traditional uses among the public.
Result and Discussion: Alkanna spp. have been used among the public since ancient times for the treatment of dermatological disorders, jaundice, kidney stones and for its wound healing, antinociceptive, anti-inflammatory, antibacterial, antiseptic and astringent effects. It has been observed that there are important biological activity studies on the chemical contents and active ingredients of Alkanna spp. and effective results have been obtained. According to the literatüre data, the Alkanna spp. may be an important candidate for drug development potential in the future.
Destekleyen Kurum
University of Health Sciences Scientific Research Projects Unit
Teşekkür
This study was produced from the master thesis. The authors would like to thank the University of Health Sciences Scientific Research Projects Unit for their support in funding this project (id: 2022/022).
Kaynakça
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ALKANNA TAUSCH CİNSİNİN KİMYASAL BİLEŞİMİ, BİYOLOJİK AKTİVİTELERİ VE GELENEKSEL KULLANIMLARINA GENEL BİR BAKIŞ
Yıl 2025,
Cilt: 49 Sayı: 2, 519 - 538, 19.05.2025
Sadi Yusufbeyoğlu
,
Ayşe Baldemir Kılıç
Öz
Amaç: Bu çalışmada, tıbbi açıdan önemli olduğu düşünülen ve halk arasında çeşitli geleneksel kullanımları bulunan Alkanna cinsinin kimyasal içerikleri ve biyolojik aktiviteleri üzerine yapılan bazı bilimsel çalışmalar özetlenmiştir.
Sonuç ve Tartışma: Alkanna türleri halk arasında eski çağlardan beri dermatolojik rahatsızlıklar, sarılık, böbrek taşı tedavisi ve yara iyileştirici, antinosiseptif, antiinflamatuar, antibakteriyel, antiseptik ve büzücü etkileri nedeniyle kullanılmaktadır. Alkanna türlerinin kimyasal içerikleri ve aktif bileşenleri üzerinde önemli biyolojik aktivite çalışmaları yapıldığı ve etkili sonuçlar elde edildiği gözlemlenmiştir. Literatür verilerine göre, Alkanna türleri gelecekte ilaç geliştirme potansiyeli için önemli bir aday olabilir.
Kaynakça
- 1. Yuan, H., Ma, Q., Ye, L., Piao, G. (2016). The traditional medicine and modern medicine from natural products. Molecules, 21(5), 559. [CrossRef]
- 2. Singh, R. (2015). Medicinal plants: A review. Journal of Plant Sciences, 3(1), 50-55.
- 3. Abdel-Gelil, O.E., Atwa, N.A., Moustafa, A.R.A., Mansour, S.R. (2019). Alkanna species: A promising herbal medicine and its uses. Journal of Food Science and Nutrition Research, 2(4), 309-315. [CrossRef]
- 4. Huu Tung, N., Du, G.J., Wang, C.Z., Yuan, C.S., Shoyama, Y. (2013). Naphthoquinone components from Alkanna tinctoria (L.) Tausch show significant antiproliferative effects on human colorectal cancer cells. Phytotherapy Research, 27(1), 66-70. [CrossRef]
- 5. Khan, R.A., Awan, A.K., Ahmed, M., Alkreathy, H., Gul, A., Khan, A.M., Mahmood, A., Khan, A., Ul Haq, M.N., Alzahrani, K.S. (2022). In-vitro antioxidant, antidiabetic activities and phytotoxic profile of Alkanna tinctoria (Boraginaceae). Journal of Pharmaceutical Research International, 36-42. [CrossRef]
- 6. Assimopoulou, A.N., Papageorgiou, V.P. (2005). Radical scavenging activity of Alkanna tinctoria root extracts and their main constituents, hydroxynaphthoquinones. Phytotherapy Research, 19(2), 141-147. [CrossRef]
- 7. Sengul, M., Yildiz, H., Gungor, N., Cetin, B., Eser, Z., Ercisli, S. (2009). Total phenolic content, antioxidant and antimicrobial activities of some medicinal plants. Pakistan Journal of Pharmaceutical Sciences, 22(1).
- 8. Mahomoodally, M.F., Zengin, G., Sinan, K.I., Ak, G., Sadeer, N.B., Angeloni, S., Mustafa, A.M., Caprioli, G., Maggi, F., Cakilcioglu, U., Kaplan, A., Babacan, E.Y., Bouyahya, A., Darendelioglu, E. (2021). Two medicinal plants (Alkanna trichophila and Convolvulus galaticus) from Turkey: Chemical Characterization and Biological Perspectives. Chemistry & Biodiversity, 18(10), e2100356. [CrossRef]
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