Examination of patients admitted to a university hospital with methanol intoxication

Abstract

Objective: The aim of this study is to evaluate the demographic data, clinical features and laboratory findings of patients followed up with methanol poisoning in our internal medicine clinic. In addition, to examine the data of the patients followed in our intensive care unit and to contribute to the literature in this direction. Material and Method: In this study, 21 patients diagnosed with methanol intoxication who were hospitalized in the internal medicine clinic of our hospital between 01.01.2019 and 01.04.2022 were included. Demographic information of the patients, initial complaints, accompanying symptoms, laboratory results, blood gas values, intensive care unit requirements, mechanical ventilation needs, length of hospital stay and whether they received hemodialysis treatment were recorded from the hospital automation system. Results: 21 patients were included in the study. The mean time for patients to apply to the hospital after drinking alcohol was calculated as 31.42±4.27 hours. The mean hospital stay was 3.0±1.02 days. While 12 patients were followed up in the intensive care unit, it was found that 6 patients needed mechanical ventilation and 9 patients needed hemodialysis. Glucose, creatinine, acetyl aminotransferase (AST), partial carbon dioxide pressure (PaCO2), lactate, anion gap and base gap were found to be statistically significantly higher in the group treated in the intensive care unit (p<0.05). When the blood gas parameters at the time of admission were compared between the groups who received and did not receive hemodialysis treatment of the patients who presented with methanol intoxication, pH, lactate, anion gap and base deficit were found to be statistically significantly higher (p=0.001). Conclusion: Hyperglycemia, increased serum creatinine value and metabolic acidosis were found to be significantly different in patients hospitalized in the intensive care unit

Keywords

• Methanol
• intensive care unit
• hemodialysis

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