Evaluation of abdominal vascular structures by multidetector computed tomography in Crimean–Congo hemorrhagic fever patients

Abstract

Aim: This study aims to determine whether Crimean–Congo Hemorrhagic Fever (CCHF) has effects on abdominal vascular structures. Material and Method: The study group included 35 patients diagnosed with CCHF. The control group included 35 patients with symptoms such as dyspepsia, pelvic pain, and abdominal pain who underwent multidetector computed tomography (MDCT) and whose MDCT examinations were reported as completely normal. This is a retrospective study and patients admitted to the hospital between May 2016 and April 2022 were included in the study. The patient group and control group were compared in terms of liver size, splenic size, and portal vein (PV), hepatic artery (HA), splenic vein (SV), splenic artery (SA), superior mesenteric vein (SMV) and superior mesenteric artery (SMA) diameters. Results: The liver size, splenic size, and PV, HA, and SA diameters in the patient group were significantly higher than those in the control group (p<0.001). While the SV, SMV, and SMA diameters were higher in the patient group than in the control group, the differences were not significant (p>0.05). Conclusion: Our study shows that abdominal vascular structures are affected in CCHF patients.

Keywords

• Crimean–Congo hemorrhagic fever
• multidetector computed tomography
• portal vein
• superior mesenteric vein

Kırım Kongo kanamalı ateşi hastalarında abdominal vasküler yapıların çokkesitli bilgisayarlı tomografi ile değerlendirilmesi

Abstract

Keywords

• Crimean–Congo Hemorrhagic Fever
• Multidetector computed tomography
• Portal vein
• Superior mesenteric vein

References

1. Aslam S, Latif M.S, Daud M, et al. Crimean-Congo hemorrhagic fever: risk factors and control measures for the infection abatement. Biomed Rep 2016; 4: 15–20.
2. Eifan S, Schnettler E, Dietrich I, et al. Non-structural proteins of arthropod-borne bunyaviruses: roles and functions. Viruses 2013; 5: 2447–68.
3. Chinikar S, Goya M, Shirzadi M, et al. Surveillance and laboratory detection system of Crimean Congo haemorrhagic fever in Iran. Transbound Emerg Dis 2008; 55: 200–4.
4. Leblebicioglu H, Ozaras R, Irmak H, et al. Crimean-Congo hemorrhagic fever in turkey: current status and future challenges. Antiviral Res 2016; 126: 21–34.
5. Flick R, Whitehouse CA. Crimean-Congo hemorrhagic fever virus. Curr Mol Med 2005; 5: 753–60.
6. Çeviker AS, Yılmaz M, Uyar C, et al. Bibliometric analysis of scientific research on Crimean-Congo hemorrhagic fever in Turkey. J Med Sci 2021; 7: 97-102.
7. Aktas T, Aktas F¸ Ozmen Z, et al. Does Crimean-Congo hemorrhagic fever cause a vasculitic reaction with pulmonary artery enlargement and acute pulmonary hypertension? Lung 2016; 194: 807–12.
8. 8.Gargili A, Estrada-Peña A, Spengler J.R, et al. The role of ticks in the maintenance and transmission of Crimean-Congo hemorrhagic fever virus: review of published field and laboratory studies. Antiviral Res 2017; 144: 93–119.

9. Karavaş E, Karakeçili F. Evaluation of portal vein doppler findings in patients with Crimean–Congo hemorrhagic fever. Medicina 2019; 55: 146
10. Ozmen Z, Albayrak E, Ozmen ZC, et al. The evaluation of abdominal findings in Crimean-Congo hemorrhagic fever. Abdom Radiol 2016; 41: 384–90.
11. Özmen Z, Parlak Z. Abdominal US findings of Crimean-Congo hemorrhagic fever. J Contemp Med 2020; 10: 261-5.
12. Babaoğlu O, Alıcıoğlu B, Sacit E. Yemekten sonra içilen sigaranın superior mezenterik arter ve portal ven hemodinamiğine etkisi: Doppler ultrasonografi çalışması. MarmaraMed J 2011; 24: 187-91.
13. Ergonul O. Crimean-Congo hemorrhagic fever virus: new outbreaks, new discoveries. Curr Opin Virol 2012; 2: 215–20.
14. Whitehouse CA. Crimean-Congo hemorrhagic fever. Antivir Res 2004; 64: 145–60.
15. Shenichnaya NY, Nenadskaya SA. Probable Crimean-Congo hemorrhagic fever virus transmission occurred afteraerosol-generating medical procedures in Russia: nosocomial cluster. Int J Infect Dis 2015; 33: 120–2.
16. Sannikova IV, Pacechnikov VD, Maleev VV. Respiratory lesions in Crimean-Congo haemorrhagic fever. Ter Arkh 2007; 79: 20–3.
17. Papa A, Tsergouli K, Çağlayık DY, et al. Cytokines as biomarkers of Crimean-Congo hemorrhagic fever. J Med Virol 2016; 88: 21-7.
18. Aktaş F, Aktaş T. The pulmonary findings of Crimean–Congo hemorrhagic fever patients with chest X‑ray assessments. La radiologia medica 2019; 124: 826–32.
19. Karavaş E, Karakecili F. Common carotid, internal carotid and vertebral artery Doppler ultrasonography findings in patients with Crimean-Congo haemorrhagic fever. Klimik Derg 2018; 31: 195–9.
20. Salk I, Kaya A, Cetin, G, et al. Doppler ultrasonographic evaluation of the carotid and vertebral arteries in children with Crimean-Congo hemorrhagic fever. Minerva Pediatr 2015; 67: 299–305.