Research Article

Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study

Volume: 8 Number: 5 September 16, 2025
TR EN

Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study

Abstract

Aims: The objective of the present study was to evaluate the anxiety levels of pregnant women who were admitted for combined first trimester screening test, and to determine the effect of screening results on maternal anxiety. Methods: The present study was carried out prospectively between March and June 2025, and comprised 148 pregnant women. The Spielberger State-Trait Anxiety Inventory was utilised in order to evaluate the participants’ state (STAI-I) and trait (STAI-II) anxiety levels. The STAI-Ia and STAI-II were administered to participants at their first admission, and first-trimester screening was performed. Following the counselling of first trimester screening results the State Anxiety Index (STAI-Ib) was re-administered to the participants. Changes in participants’ anxiety levels were evaluated. Results: The mean pre-screening state anxiety scores (STAI-Ia) of the patients were higher than their trait anxiety scores (STAI-II) (39.80±6.08 and 36.68±4.70 respectively; p<0.001). A total of 12 patients (13.9%) exhibited positive results in their first trimester screening tests. Patients with positive test results had higher state anxiety scores after first-trimester screening and counselling (STAI-Ib), compared to pre-screening scores (STAI-Ia) (40.00±7.26 vs. 43.25±7.38, p=0.003). 75% of the patients with positive test results demonstrated a probable clinical anxiety score. In patients with negative test result, state anxiety scores reduced compared to pre-sceening scores (39.79±6.00 vs. 36.93±5.27, p<0.001). Conclusion: Admission for first trimester screening has been shown to induce state anxiety in the patients. Social and psychological support should be provided to prevent the negative effects of maternal anxiety, especially in patients with positive screening results.

Keywords

Supporting Institution

None

Ethical Statement

Ethical approval for the study was obtained from the Ethics Committee of Yozgat Bozok University (Date: 05.03.2025 No: 2025-GOKAEK-255_05.03.2025-370).

Thanks

The authors would like to express their gratitude to all the obstetricians at Yozgat City Hospital for their invaluable contributions in recruiting participants for the study.

References

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  7. Fischbein RL, Nicholas L, Kingsbury DM, Falletta LM, Baughman KR, VanGeest J. State anxiety in pregnancies affected by obstetric complications: a systematic review. J Affect Disord. 2019;257:214-240. doi:10.1016/j.jad.2019.07.007
  8. Madigan S, Oatley H, Racine N, et al. A meta-analysis of maternal prenatal depression and anxiety on child socioemotional development. J Am Acad Child Adolesc Psychiatry. 2018;57(9):645-657.e8. doi:10.1016/j.jaac.2018.06.012

Details

Primary Language

English

Subjects

Obstetrics and Gynaecology

Journal Section

Research Article

Publication Date

September 16, 2025

Submission Date

June 3, 2025

Acceptance Date

July 29, 2025

Published in Issue

Year 2025 Volume: 8 Number: 5

APA
Eyisoy, Ö. G., & Sandal, K. (2025). Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study. Journal of Health Sciences and Medicine, 8(5), 794-799. https://doi.org/10.32322/jhsm.1709742
AMA
1.Eyisoy ÖG, Sandal K. Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study. J Health Sci Med / JHSM. 2025;8(5):794-799. doi:10.32322/jhsm.1709742
Chicago
Eyisoy, Ömer Gökhan, and Kemal Sandal. 2025. “Does First Trimester Prenatal Screening Impact on Maternal Anxiety? A Prospective Cohort Study”. Journal of Health Sciences and Medicine 8 (5): 794-99. https://doi.org/10.32322/jhsm.1709742.
EndNote
Eyisoy ÖG, Sandal K (September 1, 2025) Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study. Journal of Health Sciences and Medicine 8 5 794–799.
IEEE
[1]Ö. G. Eyisoy and K. Sandal, “Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study”, J Health Sci Med / JHSM, vol. 8, no. 5, pp. 794–799, Sept. 2025, doi: 10.32322/jhsm.1709742.
ISNAD
Eyisoy, Ömer Gökhan - Sandal, Kemal. “Does First Trimester Prenatal Screening Impact on Maternal Anxiety? A Prospective Cohort Study”. Journal of Health Sciences and Medicine 8/5 (September 1, 2025): 794-799. https://doi.org/10.32322/jhsm.1709742.
JAMA
1.Eyisoy ÖG, Sandal K. Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study. J Health Sci Med / JHSM. 2025;8:794–799.
MLA
Eyisoy, Ömer Gökhan, and Kemal Sandal. “Does First Trimester Prenatal Screening Impact on Maternal Anxiety? A Prospective Cohort Study”. Journal of Health Sciences and Medicine, vol. 8, no. 5, Sept. 2025, pp. 794-9, doi:10.32322/jhsm.1709742.
Vancouver
1.Ömer Gökhan Eyisoy, Kemal Sandal. Does first trimester prenatal screening impact on maternal anxiety? A prospective cohort study. J Health Sci Med / JHSM. 2025 Sep. 1;8(5):794-9. doi:10.32322/jhsm.1709742

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