İnfantil hipertrofik pilor stenozu olgularının klinik ve laboratuar bulgularının incelenmesi

Abstract

Giriş: İnfantil hipertrofik pilor stenozu (İHPS), bebeklerde yaşamın erken döneminde cerrahi müdahale gerektiren en sık gastrointestinal hastalıktır. Etyolojisi tam olarak bilinmemekle birlikte erkek cinsiyet, biberonla beslenme ve ilk çocuk olma gibi risk faktörleri tanımlanmıştır. Bu çalışmada, İHPS’li hastaların klinik ve laboratuvar bulgularını değerlendirmek ve literatüre katkıda bulunmak amaçlanmıştır. Metodoloji: 2012-2024 yılları arasında Düzce Üniversitesi Araştırma ve Uygulama Hastanesi, çocuk sağlığı ve hastalıkları kliniklerinde İHPS tanısı alan 19 olgu retrospektif olarak incelenmiştir. Olguların demografik özellikleri, başvuru şikayetleri, laboratuvar sonuçları ve doğum öyküleri analiz edilmiştir. Tanımlayıcı istatistikler ve korelasyon analizleri SPSS 25 programı kullanılarak yapılmıştır. Sonuçlar: Olguların %78,9’u erkekti, median tanı yaşı 42 gündü. Olguların %47,4’ü biberonla besleniyordu ve %47,4’ü ilk çocuktu. Kusma tüm hastalarda görülürken, %68,4’ünde kilo alamama şikayeti vardı. Hipokloremi oranı %42,1 olarak saptandı. Anne yaşı ile semptom süresi arasında orta düzeyde negatif korelasyon bulundu. Sonuç: İHPS tanı ve tedavisinde erken farkındalık hayati öneme sahiptir. Sağlık çalışanlarının bu konuda eğitilmesi, erken tanı ve tedavi başarısını artıracaktır. Çalışmamız, İHPS’nin risk faktörleri ve klinik özelliklerine dair değerli bilgiler sunmaktadır.

Keywords

• İnfantil hipertrofik pilor stenozu
• Metabolik alkaloz
• Safrasız kusma
• Zeytin belirtisi

Evaluation of clinical and laboratory findings in cases of infantile hypertrophic pyloric stenosis

Abstract

Aims: Infantile hypertrophic pyloric stenosis (IHPS) is the most common gastrointestinal disorder in early infancy that requires surgical intervention. Although its etiology is not fully understood, several risk factors have been identified, including male sex, bottle feeding, and being a first-born child. The aim of this study was to evaluate the clinical and laboratory findings of patients with IHPS and to contribute to the existing literature. Methods: This study retrospectively analyzed 19 cases of IHPS diagnosed from 2012 to 2024 at the Department of Pediatrics, Düzce University Research and Training Hospital. Demographic characteristics, presenting complaints, laboratory results, and birth histories of the patients were analyzed. Descriptive statistics and correlation analyses were performed using SPSS version 25. Results: Of the patients, 78.9% were male, with a median age at diagnosis of 42 days. Bottle feeding was observed in 47.4% of cases, and 47.4% were first-born children. Vomiting was present in all patients, while 68.4% had complaints of poor weight gain. The rate of hypochloremia was 42.1%. A moderate negative correlation was found between maternal age and the duration of symptoms. Conclusion: Early recognition is crucial in the diagnosis and management of IHPS. Training healthcare professionals on this condition may improve early diagnosis and treatment outcomes. Our study provides valuable insights into the risk factors and clinical characteristics of IHPS.

Keywords

• Infantile hypertrophic pyloric stenosis
• metabolic alkalosis
• olive sign
• nonbilious vomiting

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