Research Article

Cardiac surgery nurses' knowledge of warfarin: evaluation of a training activity

Volume: 9 Number: 2 March 12, 2026
TR EN

Cardiac surgery nurses' knowledge of warfarin: evaluation of a training activity

Abstract

Aims: The aim of this study is to evaluate the effectiveness of the training provided to cardiac surgery nurses regarding warfarin use. Methods: This pre-test-post-test quasi-experimental study was conducted between June and July 2025 at the department of cardiovascular surgery of a university hospital. The sample consisted of 30 nurses working in the clinic and intensive care unit who volunteered to participate in the study. As part of the research, nurses were educated on warfarin use, and their knowledge was measured before and after the training to evaluate the effectiveness of the training. Data were analysed using SPSS 25.0. Descriptive statistics were calculated, and pre- and post-test scores were compared using the Wilcoxon signed-rank test. Results: The average age of the nurses participating in the study was 33.30±6.62 years. The average pre-training knowledge score of nurses regarding warfarin use was 15.00±2.74, while the post-training score increased to 18.03±1.29. The average knowledge score of nurses regarding warfarin-drug interactions before training was 13.40±14.40, while after training it was 41.80±10.43, and the average knowledge score regarding warfarin-food-herb interactions increased from 9.73±5.51 to 24.60±11.05. According to the Wilcoxon signed-rank test results, statistically significant increases were observed in nurses’ knowledge scores regarding warfarin use and, warfarin–drug interactions, and warfarin–food–herb interactions after the training (p<0.001). The large effect sizes indicate that the training had a strong impact across all knowledge domains. Conclusion: This study found that cardiac surgery nurses had a sufficient level of knowledge regarding warfarin use but insufficient knowledge about drug, food and herb interactions; however, the educational intervention led to statistically significant improvements with large effect sizes across all knowledge domains.

Keywords

References

  1. Ehsani M, Farahani MA, Haghani S, Khaleghparast S, Memar MM. Assessment of knowledge and practice of cardiovascular nurses regarding warfarin. J Educ Health Promot. 2022;11:270. doi:10.4103/jehp.jehp_1240_21
  2. Chang S, Lombardo A, Smith I, Lawler S, He C, Stroebel A. Early use of non-vitamin K antagonist oral anticoagulants after cardiac surgery compared with warfarin for postoperative atrial fibrillation. ANZ J Surg. 2025;95(6):1135-1141. doi:10.1111/ans.70045
  3. Schloeglhofer T, Marschuetz A, Combs P, et al. Quality of anticoagulation with phenprocoumon and warfarin in left ventricular assist device patients: a multicenter study. ASAIO J. 2023;69(6):595-601. doi:10.1097/MAT.0000000000001895
  4. Zhu Z, Li C, Shen J, et al. New internet-based warfarin anticoagulation management approach after mechanical heart valve replacement: prospective, multicenter, randomized controlled trial. J Med Internet Res. 2021;23(8):e29529. doi:10.2196/29529
  5. Ge B, Zhang Z, Zuo Z. Updates on the clinical evidenced herb-warfarin interactions. Evid Based Complement Alternat Med. 2014;2014:957362. doi:10.1155/2014/957362
  6. Osuala EC, Ojewole EB. Knowledge, attitudes and practices of healthcare professionals regarding drug–food interactions: a scoping review. Int J Pharm Pract. 2021;29(5):406-415. doi:10.1093/ijpp/riab049
  7. Li SL, Zhou SH, Lin YJ. The value of continuous nursing in patients after cardiac mechanical valve replacement. J Cardiothorac Surg. 2020;15(1): 299. doi:10.1186/s13019-020-01326-5
  8. Zandi S, Imani B, Gholamreza S. Self-care training and informational support of patients with a mechanical heart valve on the international normalized ratio and bleeding complications. Kardichir Torakochirurgis Pol. 2021;18(2):80-86. doi:10.5114/kitp.2021.107468

Details

Primary Language

English

Subjects

Cardiovascular Surgery

Journal Section

Research Article

Publication Date

March 12, 2026

Submission Date

November 28, 2025

Acceptance Date

January 22, 2026

Published in Issue

Year 2026 Volume: 9 Number: 2

APA
Çeliktürk Doruker, N., Oktav Tönbül, T., Sarp, A., & Akyüz, Ö. (2026). Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity. Journal of Health Sciences and Medicine, 9(2), 344-354. https://doi.org/10.32322/jhsm.1831950
AMA
1.Çeliktürk Doruker N, Oktav Tönbül T, Sarp A, Akyüz Ö. Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity. J Health Sci Med / JHSM. 2026;9(2):344-354. doi:10.32322/jhsm.1831950
Chicago
Çeliktürk Doruker, Nihal, Tuğba Oktav Tönbül, Aslı Sarp, and Özlem Akyüz. 2026. “Cardiac Surgery Nurses’ Knowledge of Warfarin: Evaluation of a Training Activity”. Journal of Health Sciences and Medicine 9 (2): 344-54. https://doi.org/10.32322/jhsm.1831950.
EndNote
Çeliktürk Doruker N, Oktav Tönbül T, Sarp A, Akyüz Ö (March 1, 2026) Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity. Journal of Health Sciences and Medicine 9 2 344–354.
IEEE
[1]N. Çeliktürk Doruker, T. Oktav Tönbül, A. Sarp, and Ö. Akyüz, “Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity”, J Health Sci Med / JHSM, vol. 9, no. 2, pp. 344–354, Mar. 2026, doi: 10.32322/jhsm.1831950.
ISNAD
Çeliktürk Doruker, Nihal - Oktav Tönbül, Tuğba - Sarp, Aslı - Akyüz, Özlem. “Cardiac Surgery Nurses’ Knowledge of Warfarin: Evaluation of a Training Activity”. Journal of Health Sciences and Medicine 9/2 (March 1, 2026): 344-354. https://doi.org/10.32322/jhsm.1831950.
JAMA
1.Çeliktürk Doruker N, Oktav Tönbül T, Sarp A, Akyüz Ö. Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity. J Health Sci Med / JHSM. 2026;9:344–354.
MLA
Çeliktürk Doruker, Nihal, et al. “Cardiac Surgery Nurses’ Knowledge of Warfarin: Evaluation of a Training Activity”. Journal of Health Sciences and Medicine, vol. 9, no. 2, Mar. 2026, pp. 344-5, doi:10.32322/jhsm.1831950.
Vancouver
1.Nihal Çeliktürk Doruker, Tuğba Oktav Tönbül, Aslı Sarp, Özlem Akyüz. Cardiac surgery nurses’ knowledge of warfarin: evaluation of a training activity. J Health Sci Med / JHSM. 2026 Mar. 1;9(2):344-5. doi:10.32322/jhsm.1831950

Interuniversity Board (UAK) Equivalency: Article published in Ulakbim TR Index journal [10 POINTS], and Article published in other (excuding 1a, b, c) international indexed journal (1d) [5 POINTS].

The Directories (indexes) and Platforms we are included in are at the bottom of the page.

Note: Our journal is not WOS indexed and therefore is not classified as Q.

You can download Council of Higher Education (CoHG) [Yüksek Öğretim Kurumu (YÖK)] Criteria) decisions about predatory/questionable journals and the author's clarification text and journal charge policy from your browser. https://dergipark.org.tr/tr/journal/2316/file/4905/show







The indexes of the journal are ULAKBİM TR Dizin, ICI World of Journals, DOAJ, Directory of Research Journals Indexing (DRJI), General Impact Factor, ASOS Index, WorldCat (OCLC), MIAR, OpenAIRE, Türkiye Citation Index, Türk Medline Index, InfoBase Index, Scilit, etc.

       images?q=tbn:ANd9GcRB9r6zRLDl0Pz7om2DQkiTQXqDtuq64Eb1Qg&usqp=CAU

500px-WorldCat_logo.svg.png

atifdizini.png

logo_world_of_journals_no_margin.png

images?q=tbn%3AANd9GcTNpvUjQ4Ffc6uQBqMQrqYMR53c7bRqD9rohCINkko0Y1a_hPSn&usqp=CAU

doaj.png  

images?q=tbn:ANd9GcSpOQFsFv3RdX0lIQJC3SwkFIA-CceHin_ujli_JrqBy3A32A_Tx_oMoIZn96EcrpLwTQg&usqp=CAU

ici2.png

asos-index.png

drji.png





The platforms of the journal are Google Scholar, CrossRef (DOI), ResearchBib, Open Access, COPE, ICMJE, NCBI, ORCID, Creative Commons, etc.

COPE-logo-300x199.jpgimages?q=tbn:ANd9GcQR6_qdgvxMP9owgnYzJ1M6CS_XzR_d7orTjA&usqp=CAU

icmje_1_orig.png

cc.logo.large.png

ncbi.pngimages?q=tbn:ANd9GcRBcJw8ia8S9TI4Fun5vj3HPzEcEKIvF_jtnw&usqp=CAU

ORCID_logo.png

1*mvsP194Golg0Dmo2rjJ-oQ.jpeg


Our Journal using the DergiPark system indexed are;

Ulakbim TR Dizin,  Index Copernicus, ICI World of JournalsDirectory of Research Journals Indexing (DRJI), General Impact FactorASOS Index, OpenAIRE, MIAR,  EuroPub, WorldCat (OCLC)DOAJ,  Türkiye Citation Index, Türk Medline Index, InfoBase Index


Our Journal using the DergiPark system platforms are;

Google, Google Scholar, CrossRef (DOI), ResearchBib, ICJME, COPE, NCBI, ORCID, Creative Commons, Open Access, and etc.


Journal articles are evaluated as "Double-Blind Peer Review". 

Our journal has adopted the Open Access Policy and articles in JHSM are Open Access and fully comply with Open Access instructions. All articles in the system can be accessed and read without a journal user.  https//dergipark.org.tr/tr/pub/jhsm/page/9535

Journal charge policy   https://dergipark.org.tr/tr/pub/jhsm/page/10912

Our journal has been indexed in DOAJ as of May 18, 2020.

Our journal has been indexed in TR-Dizin as of March 12, 2021.


17873

Articles published in Journal of Health Sciences and Medicine have open access and are licensed under the Creative Commons CC BY-NC-ND 4.0 International License.