Research Article
BibTex RIS Cite

Energy-based devices versus conventional ligation in thyroid surgery: operative efficiency and postoperative outcomes

Year 2026, Volume: 9 Issue: 2 , 287 - 292 , 12.03.2026
https://doi.org/10.32322/jhsm.1848683
https://izlik.org/JA34ZK88TB

Abstract

Aims: This study aimed to compare the operative efficiency and postoperative outcomes of thyroidectomy procedures performed using energy-based devices (EBDs) versus conventional ligation techniques.
Methods: A retrospective analysis was conducted on 443 patients who underwent total thyroidectomy between January 2019 and August 2025. Patients were divided into two groups: those operated with EBDs (n=162) and those with conventional ligation (n=281). Demographic data, operative time, drain removal time, length of hospital stay, postoperative calcium and parathyroid hormone (PTH) levels, hypocalcemia incidence, recurrent laryngeal nerve injury, and histopathological findings were evaluated. Statistical analyses were performed using non-parametric tests, with p<0.05 considered significant.
Results: The median operative time was significantly shorter in the EBD group compared to the ligation group (55 vs. 60 minutes, p<0.001). However, both the drain removal time and hospital stay were significantly shorter in the ligation group (p<0.001 for both). There were no significant differences between groups regarding postoperative calcium and PTH levels (p=0.144 and p=0.123, respectively). The incidence of transient or permanent hypocalcemia and postoperative hoarseness was comparable between the two groups. Histopathological distribution differed significantly (p=0.017), with a higher rate of papillary thyroid carcinoma in the EBD group.
Conclusion: EBDs are associated with a statistically shorter operative time in thyroidectomy without increasing complication rates compared to conventional ligation. However, the shorter drain removal and hospitalization durations in the ligation group indicate that the use of EBDs does not necessarily improve all clinical parameters. Further studies focusing on device-specific performance, standardized application parameters, and cost-effectiveness may help to better define the optimal use of EBDs in routine clinical practice.

References

  • Gasparri, G. History of thyroid surgery. In: Testini, M., Gurrado, A. (eds) Thyroid Surgery. Updates in Surgery. Springer, Cham.2024.
  • Hong PK, Pathak A, Shirali AS. Predictors of postoperative complications following thyroidectomy: a systematic review. Surg Pract Sci. 2024;18:100252. doi:10.1016/j.sipas.2024.100252
  • Ajit-Roger E, Hier J, Mascarella M, et al. Factors increasing the likelihood of postoperative hematomas following thyroid surgery. Head Neck. 2025;47(7):1897-1906. doi:10.1002/hed.28096
  • Al-Hakami H, Al Garni M. Incidence and risk factors for recurrent laryngeal nerve injury after thyroid surgery. Egypt J Otolaryngol. 2024; 40(1):92.
  • Hsu HW, Huang SH, Lee SH, et al. Impact of intraoperative interventions on hypocalcemia post-total thyroidectomy: a meta-analysis. J Otolaryngol Head Neck Surg. 2025;54:19160216251333355. doi:10.1177/19160216251333355
  • Spartalis E, Giannakodimos A, Giannakodimos I, et al. The role of LigaSure™ and Harmonic Scalpel in the preservation of recurrent laryngeal nerve during thyroidectomy. Ann R Coll Surg Engl. 2022; 104(5):324-329. doi:10.1308/rcsann.2021.0125
  • Lee E, Tong JY, Pasick LJ, et al. Complications associated with energy-based devices during thyroidectomy from 2010-2020. World J Otorhinolaryngol Head Neck Surg. 2022;9(1):35-44. doi:10.1016/j.wjorl. 2021.04.008
  • Canu GL, Medas F, Podda F, et al. Thyroidectomy with energy-based devices: surgical outcomes and complications-comparison between Harmonic Focus, LigaSure Small Jaw and Thunderbeat Open Fine Jaw. Gland Surg. 2020;9(3):721-726. doi:10.21037/gs.2020.03.31
  • Al Saffar RS, Al Hakkak SMM, Alnajim AA, Al Hakkak MS. Comparative study of energy-based technologies in thyroidectomy: Harmonic focus, ligasure tiny jaw, and conventional techniques at a single institution. Wiad Lek. 2025;78(2):376-380. doi:10.36740/WLek/ 200406
  • Montori G, Botteri E, Ortenzi M, et al. Systematic review and meta-analysis of the use of high-energy devices for thyroid surgery.Langenbecks Arch Surg. 2024;409(1):217. doi:10.1007/s00423-024-03399-5
  • Lombardi CP, Raffaelli M, Cicchetti A, et al. The use of "harmonic scalpel" versus "knot tying" for conventional "open" thyroidectomy: results of a prospective randomized study. Langenbecks Arch Surg. 2008; 393(5):627-631. doi:10.1007/s00423-008-0380-9
  • Lang BH, Ng SH, Lau LL, Cowling BJ, Wong KP. A systematic review and meta-analysis comparing the efficacy and surgical outcomes of total thyroidectomy between harmonic scalpel versus ligasure. Ann Surg Oncol. 2013;20(6):1918-1926. doi:10.1245/s10434-012-2849-6
  • Lee JS, Lee JS, Yun HJ, et al. No change in complications following thyroidectomy despite increase in thyroid cancer surgeries: a meta-regression analysis. Yonsei Med J. 2024;65(6):348-355. doi:10.3349/ymj. 2023.0266
  • Chuang CH, Huang TY, Hwang TZ, et al. Accumulation of experience and newly developed devices can improve the safety and voice outcome of total thyroidectomy for graves' disease. J Clin Med. 2022;11(5):1298. doi:10.3390/jcm11051298
There are 14 citations in total.

Details

Primary Language English
Subjects General Surgery
Journal Section Research Article
Authors

Fırat Canlıkarakaya 0000-0003-4858-7480

Bedri Burak Sucu 0000-0002-0401-021X

Sezai Kantar 0000-0001-6329-3494

Sabiha Nur Özmen 0000-0002-4669-0962

Hüseyin Turap 0000-0001-7491-3134

Cengiz Ceylan 0000-0003-3471-8726

Submission Date December 24, 2025
Acceptance Date January 11, 2026
Publication Date March 12, 2026
DOI https://doi.org/10.32322/jhsm.1848683
IZ https://izlik.org/JA34ZK88TB
Published in Issue Year 2026 Volume: 9 Issue: 2

Cite

AMA 1.Canlıkarakaya F, Sucu BB, Kantar S, Özmen SN, Turap H, Ceylan C. Energy-based devices versus conventional ligation in thyroid surgery: operative efficiency and postoperative outcomes. J Health Sci Med / JHSM. 2026;9(2):287-292. doi:10.32322/jhsm.1848683

Interuniversity Board (UAK) Equivalency: Article published in Ulakbim TR Index journal [10 POINTS], and Article published in other (excuding 1a, b, c) international indexed journal (1d) [5 POINTS].

The Directories (indexes) and Platforms we are included in are at the bottom of the page.

Note: Our journal is not WOS indexed and therefore is not classified as Q.

You can download Council of Higher Education (CoHG) [Yüksek Öğretim Kurumu (YÖK)] Criteria) decisions about predatory/questionable journals and the author's clarification text and journal charge policy from your browser. https://dergipark.org.tr/tr/journal/2316/file/4905/show







The indexes of the journal are ULAKBİM TR Dizin, ICI World of Journals, DOAJ, Directory of Research Journals Indexing (DRJI), General Impact Factor, ASOS Index, WorldCat (OCLC), MIAR, OpenAIRE, Türkiye Citation Index, Türk Medline Index, InfoBase Index, Scilit, etc.

       images?q=tbn:ANd9GcRB9r6zRLDl0Pz7om2DQkiTQXqDtuq64Eb1Qg&usqp=CAU

500px-WorldCat_logo.svg.png

atifdizini.png

logo_world_of_journals_no_margin.png

images?q=tbn%3AANd9GcTNpvUjQ4Ffc6uQBqMQrqYMR53c7bRqD9rohCINkko0Y1a_hPSn&usqp=CAU

doaj.png  

images?q=tbn:ANd9GcSpOQFsFv3RdX0lIQJC3SwkFIA-CceHin_ujli_JrqBy3A32A_Tx_oMoIZn96EcrpLwTQg&usqp=CAU

ici2.png

asos-index.png

drji.png





The platforms of the journal are Google Scholar, CrossRef (DOI), ResearchBib, Open Access, COPE, ICMJE, NCBI, ORCID, Creative Commons, etc.

COPE-logo-300x199.jpgimages?q=tbn:ANd9GcQR6_qdgvxMP9owgnYzJ1M6CS_XzR_d7orTjA&usqp=CAU

icmje_1_orig.png

cc.logo.large.png

ncbi.pngimages?q=tbn:ANd9GcRBcJw8ia8S9TI4Fun5vj3HPzEcEKIvF_jtnw&usqp=CAU

ORCID_logo.png

1*mvsP194Golg0Dmo2rjJ-oQ.jpeg


Our Journal using the DergiPark system indexed are;

Ulakbim TR Dizin,  Index Copernicus, ICI World of JournalsDirectory of Research Journals Indexing (DRJI), General Impact FactorASOS Index, OpenAIRE, MIAR,  EuroPub, WorldCat (OCLC)DOAJ,  Türkiye Citation Index, Türk Medline Index, InfoBase Index


Our Journal using the DergiPark system platforms are;

Google, Google Scholar, CrossRef (DOI), ResearchBib, ICJME, COPE, NCBI, ORCID, Creative Commons, Open Access, and etc.


Journal articles are evaluated as "Double-Blind Peer Review". 

Our journal has adopted the Open Access Policy and articles in JHSM are Open Access and fully comply with Open Access instructions. All articles in the system can be accessed and read without a journal user.  https//dergipark.org.tr/tr/pub/jhsm/page/9535

Journal charge policy   https://dergipark.org.tr/tr/pub/jhsm/page/10912

Our journal has been indexed in DOAJ as of May 18, 2020.

Our journal has been indexed in TR-Dizin as of March 12, 2021.


17873

Articles published in Journal of Health Sciences and Medicine have open access and are licensed under the Creative Commons CC BY-NC-ND 4.0 International License.