Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association
Abstract
Aims: Periodontitis is a chronic inflammatory condition implicated in the pathogenesis of systemic diseases, including chronic kidney disease (CKD), primarily through low-grade systemic inflammatory pathways. Given the potential impact of periodontal health on CKD progression, this study aims to assess nephrologists’ awareness, attitudes, and clinical practices regarding the association between periodontal disease and CKD.
Methods: This cross-sectional study used a structured, literature-based questionnaire distributed via Google Forms to nephrologists. Participation was voluntary, and informed consent was obtained online. The survey included demographic questions and items assessing awareness, attitudes, and clinical practice approaches regarding the interrelationship between periodontal disease and CKD. A total of 144 nephrologists completed the survey. Multivariable binary logistic regression was employed to identify independent predictors of participants' oral health education status.
Results: Of the 144 nephrologists surveyed, most were aged 45–54 years, had 11–20 years of experience, and worked in university hospitals following over 100 CKD patients monthly. While general awareness of the oral–renal connection was moderate to high, many participants did not routinely take oral health histories or recognize uremic manifestations. Nonetheless, the majority reported referring patients with oral complaints to dentists. Prior training in oral health and recent dental visits were associated with higher awareness and more positive attitudes. Regression analysis identified age as a significant predictor of prior training, with nephrologists aged 35–44 and 55+ being 7.4 times more likely to have received oral health education (p=0.036).
Conclusion: Since age was identified as a significant predictor of prior training, with younger nephrologists being less likely to have received oral health education, targeted interdisciplinary programs focusing on early-career specialists are essential to bridge this knowledge gap. Furthermore, the inverse relationship between educational opinions and prior training emphasizes a strong perceived need for such interventions among untrained professionals.
Keywords
Supporting Institution
The authors did not receive support from any organization for the submitted work.
Project Number
None
Ethical Statement
This questionnaire-based study was approved by the Hamidiye Non-Interventional Scientific Research Ethics Committee (Decision No: 2025/15-3). The study was conducted in accordance with relevant guidelines and regulations.
Thanks
The authors would like to thank all participating nephrologists for their support in this research.
References
- Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Periodontol. 2018;89(Suppl 1):S159-s172. doi:10.1002/jper. 18-0006
- Mehrotra N, Singh S. Periodontitis. StatPearls. StatPearls Publishing. Copyright © 2025, StatPearls Publishing LLC.; 2025.
- Shoji T, Abe T, Matsuo H, et al. Chronic kidney disease, dyslipidemia, and atherosclerosis. J Atheroscler Thromb. 2012;19(4):299-315. doi:10. 5551/jat.10454
- Büberci R, Duranay M. Risk factors for chronic kidney disease progression in patients with solitary kidney. J Health Sci Med. 2022;5(3): 342-347. doi:10.32322/jhsm.1009811
- Luyckx VA, Tuttle KR, Garcia-Garcia G, et al. Reducing major risk factors for chronic kidney disease. Kidney Int Suppl (2011). 2017;7(2):71-87. doi:10.1016/j.kisu.2017.07.003
- Loos BG. Systemic markers of inflammation in periodontitis. J Periodontol. 2005;76(11 Suppl):2106-2115. doi:10.1902/jop.2005.76.11-S. 2106
- Kshirsagar AV, Moss KL, Elter JR, Beck JD, Offenbacher S, Falk RJ. Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk In Communities (ARIC) study. Am J Kidney Dis. 2005;45(4):650-657. doi:10.1053/j.ajkd.2004.12.009
- Fisher MA, Taylor GW, Shelton BJ, et al. Periodontal disease and other nontraditional risk factors for CKD. Am J Kidney Dis. 2008;51(1):45-52. doi:10.1053/j.ajkd.2007.09.018
Details
Primary Language
English
Subjects
Periodontics, Nefroloji
Journal Section
Research Article
Publication Date
March 12, 2026
Submission Date
December 29, 2025
Acceptance Date
March 11, 2026
Published in Issue
Year 2026 Volume: 9 Number: 2
APA
Ceylan Şen, S., Saraç Atagün, Ö., Ustaoğlu, G., Paksoy, T., & Kadıoğlu Koçak, M. G. (2026). Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association. Journal of Health Sciences and Medicine, 9(2), 544-551. https://doi.org/10.32322/jhsm.1851652
AMA
1.Ceylan Şen S, Saraç Atagün Ö, Ustaoğlu G, Paksoy T, Kadıoğlu Koçak MG. Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association. J Health Sci Med / JHSM. 2026;9(2):544-551. doi:10.32322/jhsm.1851652
Chicago
Ceylan Şen, Seval, Özlem Saraç Atagün, Gülbahar Ustaoğlu, Tuğçe Paksoy, and Meral Gülay Kadıoğlu Koçak. 2026. “Awareness, Perceptions, and Clinical Practice Approaches of Nephrologists Toward the Periodontal Disease–chronic Kidney Disease Association”. Journal of Health Sciences and Medicine 9 (2): 544-51. https://doi.org/10.32322/jhsm.1851652.
EndNote
Ceylan Şen S, Saraç Atagün Ö, Ustaoğlu G, Paksoy T, Kadıoğlu Koçak MG (March 1, 2026) Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association. Journal of Health Sciences and Medicine 9 2 544–551.
IEEE
[1]S. Ceylan Şen, Ö. Saraç Atagün, G. Ustaoğlu, T. Paksoy, and M. G. Kadıoğlu Koçak, “Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association”, J Health Sci Med / JHSM, vol. 9, no. 2, pp. 544–551, Mar. 2026, doi: 10.32322/jhsm.1851652.
ISNAD
Ceylan Şen, Seval - Saraç Atagün, Özlem - Ustaoğlu, Gülbahar - Paksoy, Tuğçe - Kadıoğlu Koçak, Meral Gülay. “Awareness, Perceptions, and Clinical Practice Approaches of Nephrologists Toward the Periodontal Disease–chronic Kidney Disease Association”. Journal of Health Sciences and Medicine 9/2 (March 1, 2026): 544-551. https://doi.org/10.32322/jhsm.1851652.
JAMA
1.Ceylan Şen S, Saraç Atagün Ö, Ustaoğlu G, Paksoy T, Kadıoğlu Koçak MG. Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association. J Health Sci Med / JHSM. 2026;9:544–551.
MLA
Ceylan Şen, Seval, et al. “Awareness, Perceptions, and Clinical Practice Approaches of Nephrologists Toward the Periodontal Disease–chronic Kidney Disease Association”. Journal of Health Sciences and Medicine, vol. 9, no. 2, Mar. 2026, pp. 544-51, doi:10.32322/jhsm.1851652.
Vancouver
1.Seval Ceylan Şen, Özlem Saraç Atagün, Gülbahar Ustaoğlu, Tuğçe Paksoy, Meral Gülay Kadıoğlu Koçak. Awareness, perceptions, and clinical practice approaches of nephrologists toward the periodontal disease–chronic kidney disease association. J Health Sci Med / JHSM. 2026 Mar. 1;9(2):544-51. doi:10.32322/jhsm.1851652
