Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia

Dilek Kurnaz; Burcu Cebeci; Betül Zehra Pirdal; Derya Büyükkayhan

Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia

Abstract

Aims: This study aimed to investigate the etiology and risk factors associated with indirect neonatal hyperbilirubinemia (INH) and their effects on the duration of hospital stay. Methods: A total of 400 term newborns with INH were included in the study. Demographic characteristics, feeding practices, total serum bilirubin levels, phototherapy duration, and length of hospital stay were recorded. Risk zones for hyperbilirubinemia were determined using the Bhutani nomogram, and the significance of associated factors was assessed using Chi-square and Fisher’s exact tests. Results: Of the 400 newborns, 51.5% were male, with a mean gestational age of 38.67±1.11 weeks and a mean birth weight of 3286.6±450.4 g. Twenty-five percent of the infants were classified in the high-risk zone for hyperbilirubinemia. Infants in the high-risk group were admitted at a significantly older postnatal age and required longer phototherapy duration compared with those in the intermediate-high risk group. Positive direct Coombs (DC) test and mixed feeding were significantly associated with prolonged phototherapy duration (>2 days). Furthermore, early-term infants were found to have a higher risk of developing severe hyperbilirubinemia. Gestational age, feeding method, DC positivity, parity, and phototherapy duration were identified as significant determinants of hospital stay. Conclusion: This study identified key risk factors associated with prolonged hospital stay in term newborns with INH, including DC positivity and mixed feeding practices. These findings highlight the importance of early identification and appropriate management of at-risk infants to reduce the severity of hyperbilirubinemia and associated hospitalization duration.

Keywords

Supporting Institution

No funding was obtained for this study.

Ethical Statement

The study was conducted in accordance with the Declaration of Helsinki after obtaining permission from the Haseki Training and Research Hospital Ethics Committee. Ethics Committee approval (No: 142-2020) was obtained.

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Details

Primary Language

English

Subjects

Neonatology

Journal Section

Research Article

Authors

Dilek Kurnaz ^*
0000-0001-9545-8820
Türkiye

Burcu Cebeci
0000-0003-1886-8126
Türkiye

Betül Zehra Pirdal
0000-0001-0127-9296
Türkiye

Derya Büyükkayhan
0000-0001-7172-0812
Türkiye

Publication Date

May 19, 2026

Submission Date

January 3, 2026

Acceptance Date

April 14, 2026

Published in Issue

Year 2026 Volume: 9 Number: 3

IZ

https://izlik.org/JA27UU94YH

Cite

RIS / Bibtex

APA

Kurnaz, D., Cebeci, B., Pirdal, B. Z., & Büyükkayhan, D. (2026). Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia. Journal of Health Sciences and Medicine, 9(3), 576-582. https://izlik.org/JA27UU94YH

AMA

1.Kurnaz D, Cebeci B, Pirdal BZ, Büyükkayhan D. Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia. J Health Sci Med / JHSM. 2026;9(3):576-582. https://izlik.org/JA27UU94YH

Chicago

Kurnaz, Dilek, Burcu Cebeci, Betül Zehra Pirdal, and Derya Büyükkayhan. 2026. “Evaluation of Factors Affecting Hospital Stay in Newborns With Hyperbilirubinemia”. Journal of Health Sciences and Medicine 9 (3): 576-82. https://izlik.org/JA27UU94YH.

EndNote

Kurnaz D, Cebeci B, Pirdal BZ, Büyükkayhan D (May 1, 2026) Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia. Journal of Health Sciences and Medicine 9 3 576–582.

IEEE

[1]D. Kurnaz, B. Cebeci, B. Z. Pirdal, and D. Büyükkayhan, “Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia”, J Health Sci Med / JHSM, vol. 9, no. 3, pp. 576–582, May 2026, [Online]. Available: https://izlik.org/JA27UU94YH

ISNAD

Kurnaz, Dilek - Cebeci, Burcu - Pirdal, Betül Zehra - Büyükkayhan, Derya. “Evaluation of Factors Affecting Hospital Stay in Newborns With Hyperbilirubinemia”. Journal of Health Sciences and Medicine 9/3 (May 1, 2026): 576-582. https://izlik.org/JA27UU94YH.

JAMA

1.Kurnaz D, Cebeci B, Pirdal BZ, Büyükkayhan D. Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia. J Health Sci Med / JHSM. 2026;9:576–582.

MLA

Kurnaz, Dilek, et al. “Evaluation of Factors Affecting Hospital Stay in Newborns With Hyperbilirubinemia”. Journal of Health Sciences and Medicine, vol. 9, no. 3, May 2026, pp. 576-82, https://izlik.org/JA27UU94YH.

Vancouver

1.Dilek Kurnaz, Burcu Cebeci, Betül Zehra Pirdal, Derya Büyükkayhan. Evaluation of factors affecting hospital stay in newborns with hyperbilirubinemia. J Health Sci Med / JHSM [Internet]. 2026 May 1;9(3):576-82. Available from: https://izlik.org/JA27UU94YH