Correction: Sex-specific linear regression models for age estimation using Cameriere’s third Molar Maturity Index (I3M): a preliminary report from Turkiye
Erratum Note
Abstract
Aims: Cameriere’s Third Molar Maturity Index (I3M) is well established for age-threshold determination, yet its application in regression-based age estimation has not been explored in the Turkish population. This study aimed to derive sex-specific linear regression models for estimating chronological age from I3M in Turkish adolescents and young adults. Methods: This retrospective cross-sectional study evaluated 200 digital panoramic radiographs of individuals aged 14-22 years. I3M was quantified on left mandibular third molars using standardized ImageJ-based measurements by a single blinded examiner (ICC=0.90). Linear regression models were constructed for the pooled sample and separately by sex. Results: I3M showed a statistically significant inverse association with chronological age in all models (p<0.001). In the pooled analysis [age=19.04 - 4.24×I3M; B=-4.24, SE=0.33, 95% CI (-4.88, -3.60)], the model accounted for 46.1% of the variance (adjusted R²=45.9%) with a standard error of estimate (SEE) of 1.65 years and a mean absolute error (MAE) of 1.34 years. Sex-stratified models showed comparable performance: females (R²=49.5%, SEE=1.64, MAE=1.36) and males (R²=41.5%, SEE=1.69, MAE=1.31), with no statistically significant difference between models (Chow test p=0.67). Conclusion: This preliminary study presents the first population-specific regression equations for I3M in Turkiye. These models may serve as a complementary forensic tool for age estimation across multiple legally relevant thresholds. However, the moderate explained variance warrants caution, and external validation in an independent Turkish sample is required before routine forensic application.
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Ethical Statement
References
- Shoukath A, Vidigal MTC, Vieira W, Paranhos LR, Mânica S, Franco A. Dental age estimation methods applied to Indian children and adolescents: a systematic review and meta-analysis. Morphologie. 2024; 108(361):100758. doi:10.1016/j.morpho.2023.100758
- Vila-Blanco N, Varas-Quintana P, Tomás I, Carreira MJ. A systematic overview of dental methods for age assessment in living individuals: from traditional to Artificial Intelligence-based approaches. Int J Legal Med. 2023;137(4):1117-1146. doi:10.1007/s00414-023-02960-z
- Rokhshad R, Nasiri F, Saberi N, et al. Deep learning for age estimation from panoramic radiographs: a systematic review and meta-analysis. J Dent. 2025;154:105560. doi:10.1016/j.jdent.2025.105560
- Cameriere R, Ferrante L, De Angelis D, Scarpino F, Galli F. The comparison between measurement of open apices of third molars and Demirjian stages to test chronological age of over 18 year olds in living subjects. Int J Legal Med. 2008;122(6):493-497. doi:10.1007/s00414-008-0279-6
- De Luca S, Pacifici A, Pacifici L, et al. Third molar development by measurements of open apices in an Italian sample of living subjects. J Forensic Leg Med. 2016;38:36-42. doi:10.1016/j.jflm.2015.11.007
- Pereira CP, Rodrigues A, Augusto D, et al. Forensic age estimation using new models of mathematical regression formula constructed with molar indexes: dental age assessment. J Stomatol. 2021;74(2):95-100. doi:10.5114/jos.2021.106540
- Kelmendi J, Cameriere R, Koçani F, Galić I, Mehmeti B, Vodanović M. The Third Molar Maturity Index in indicating the legal adult age in Kosovar population. Int J Legal Med. 2018;132(4):1151-1159. doi:10.1007/s00414-017-1761-9
- Gulsahi A, De Luca S, Cehreli SB, Tirali RE, Cameriere R. Accuracy of the third molar index for assessing the legal majority of 18 years in Turkish population. Forensic Sci Int. 2016;266:584.e1-584.e6. doi:10. 1016/j.forsciint.2016.04.034
Details
Primary Language
English
Subjects
Forensic Dentistry
Journal Section
Erratum
Publication Date
October 25, 2026
Submission Date
October 2, 2026
Acceptance Date
October 22, 2026
Published in Issue
Year 2026 Volume: 9 Number: 6




