Mean platelet volume and platelet distribution width as mortality predictors in ıntensive care unit

Abstract

Background and Aim: This study aimed to determine the mean platelet volume (MPV) and platelet distribution width (PDW) values of intensive care patients, and show the relationship between these parameters and mortality.

Material and Method: In the present study, 284 patients who were hospitalized in the intensive care unit were retrospectively analyzed. MPV and PDW values of the patients when they first hospitalized, their last MPV and PDW values before they died or were discharged, their ages and duration of hospitalization were recorded.

Results: There was no significant difference between the MPV and PDW values in the group of the patients who survived. Similarly, there was no statistically significant difference between PDWFirst and PDWLast values in the group of the patients who died (p> 0.05). However, MPVLast value increased significantly compared to MPVFirst values (p <0.05) in the group of the patients who died. MPVLast was found to be the most important factor when the age, hospitalization period, MPV and PDW values of the patients, which are associated with mortality, were compared.

Conclusion: This study showed that MPV values increased in the patients who died and that they were closely related to mortality.

Keywords

• : MPV,PDW,mortality,intensive care unit

Project Number

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Yoğun bakım ünitesinde ortalama platelet hacmi ve platelet dağılım hacminin mortaliteye etkisi

Abstract

Giriş/Amaç: Bu çalışmada genel Yoğun Bakım Ünitesi’ndeki (YBÜ) hasta populasyonunda, MPV (ortalama platelet hacmi) ve PDW (platelet dağilim hacmi) parametrelerinin mortalite ile olan ilişkisini değerlendirmeyi amaçladık.

Gereç ve Yöntem: Genel YBÜ’ de yatan 284 hasta retrospektif olarak analiz edildi. Hastaların ilk yatışlarında MPV ve PDW değerleri, ölmeden veya taburcu edilmeden önceki son MPV ve PDW değerleri, hastanede yatış süreleri ve yaşları kaydedildi.

Bulgular: Hayatta kalan hasta grubunda MPV ve PDW değerleri arasında anlamlı fark yoktu. Benzer şekilde, ölen hastaların grubunda PDWFirst ve PDWLast değerleri arasında istatistiksel olarak anlamlı fark yoktu (p> 0.05). Bununla birlikte, ölen hastaların grubunda MPVLast değeri, MPVFirst değerlerine göre anlamlı olarak arttı (p <0.05). Mortalite ile ilişkili hastaların yaş, hastanede kalış süreleri, MPV ve PDW değerleri karşılaştırıldığında en önemli faktör MPVLast olarak bulundu.

 Sonuç: Bu çalışma, ölen hastalarda MPV değerlerinin arttığını ve mortalite ile yakından ilişkili olduğunu göstermiştir.

Keywords

• MPV,PDW,mortalite,yoğun bakım ünitesi

Supporting Institution

Yok

Project Number

Yok

Thanks

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