The frequency and relationship of osteoporosis and vitamin D deficiency in the female geriatric population in Central Anatolia

Abstract

Bacground / Aims: The frequency of osteoporosis increases with age and is an important cause of mortality and morbidity due to hip fractures. The aim of our study is to determine the frequency of osteoporosis and vitamin D deficiency in female geriatric population and to investigate the relationship of vertebral and femur bone mineral densities (BMD) with vitamin D level in this population. Material and Method: The study included 457 women aged 65 years and older. Vertebra and femur bone mineral densities (BMD) and serum 25-hydroxy vitamin D3 (25 (OH) D3) levels were measured. Results: The mean age was found to be 72.4 ± 5.7 years. The mean L1-L4 and Femur neck BMD values in the participants were -2.74 ± 0.77, -2.31 ± 0.95 respectively, and the rate of osteoporosis was 72.2% (n = 330). There was no statistically significant difference between age groups in respect to frequency of osteaporosis (p = 0.58). Weak negative correlation was found between femur neck BMD value and age (r = -0.26, p <0.001). Vitamin D level was 13.00 ± 8.80 ng / ml and vitamin D deficiency was 87.4% (n = 387). There was no statistically significant difference between age groups in respect to frequency of vitamin D deficiency (p = 0.16). Similarly, no statistically significant relationship was found between osteoporosis and vitamin D deficiency (p = 0.65). Conclusion: This study suggested that geographic, cultural, and genetic factors are more important determinants in the development of osteoporosis.

Keywords

• Bone mineral density
• Central Anatolia
• female geriatric population
• vitamin D

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