Evaluation of 25-hydroxy vitamin D levels in COVID-19 positive patients

Abstract

Aim: With this study, the aim was to evaluate the serum 25-hydroxy vitamin D levels in COVID-19 positive patients. Material and Method: The study retrospectively screened the archive records for patient data from 732 patients, attending the pandemic clinic in our hospital from March 2020 to February 2021 aged over 18 years with COVID-19 positivity and serum 25-hydroxy vitamin D levels examined, with data from 360 control patients between the same dates in similar age group and without COVID-19 positivity. COVID-19 positive patients and control group patients were divided into three groups according to serum 25-hydroxy vitamin D levels (deficiency, insufficiency, and normal level). Results: Of the 732 COVID-19 positive patients included in the study, 66.4% were female (n=486) and 33.6% were male (n=246). The mean serum 25(OH)D level in the COVID-19 positive patient group was calculated as 14.2± 11.7 ng/ml. For the 360 patients included in the COVID-19 negative control group, 70% were female (n=252) and 30% were male (n=108). Mean serum 25(OH)D level in the COVID-19 negative control group was 27.6±12.1 ng/l. There was a significant difference between the groups (p=0.012). Conclusion: High rates of vitamin D deficiency and insufficiency are seen in COVID-19 positive patients. Sufficient levels of replacement for patients with low vitamin D levels will provide significant reductions in musculoskeletal system symptoms and complaints of patients. We think vitamin D is a protective vitamin for COVID-19.

Keywords

• COVID-19
• pandemic
• 25-hydroxy vitamin D
• prognosis

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