Kondroid neoplazi ile AB0 kan grupları arasında bir ilişki var mı?

Yıl 2020, Cilt: 3 Sayı: 4, 432 - 435, 22.10.2020

Fevzi Sökmen , Coşkun Ulucaköy

https://doi.org/10.32322/jhsm.785087

Öz

Amaç : AB0 ve Rh kan grupları, çeşitli malignitelerle ilişkilendirilmiştir. Bu çalışmada AB0 kan grupları ile kondroid neoplazi arasındaki ilişkinin araştırılması amaçlanmıştır. 276 kondroid neoplazili hastayı retrospektif olarak değerlendirdik.
Gereç ve Yöntem : 2014-2019 yılları arasında ameliyat edilen hastaların kan grupları ve tümör lokalizasyonu kaydedildi. Kontrol grubunu 2019 yılında hastanemize kan bağışı yapan 129 hasta oluşturdu. Ki-kare testi ile hastaların demografik özelliklerini ve kan gruplarını kontrol grubu ile karşılaştırdık.
Bulgular : Ortalama yaş, enkondroma, kondrosarkom ve kontrol grubu için sırasıyla 52 ± 14.6, 49 ± 15.9 ve 37 ± 10.3 yıldı. Tümör hem enkondrom hem de kondrosarkom hastalarında çoğunlukla distal femurda lokalizeydi. Enkondroma ve kondrosarkomlu hastalarda 0Rh (+) kan grubu oranı daha yüksek ve B (Rh (+) kan grubu oranı kontrol grubuna göre daha düşük olmasına rağmen, bu fark istatistiksel olarak anlamlı değildi.
Sonuç : A ve AB kan grubu oranları AB0 kan grupları ile kondroid neoplazi arasında ilişki yoktu. Geniş hasta serilerinde farklı benign ve malign kemik tümörlerinin AB0 ve Rh kan grupları ile ilişkisini araştıran çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

Enkondrom, kondrosarkom, AB0 kan grupları, malignite

Is there a relationship between chondroid neoplasia and AB0 blood groups?

Öz

Aim : AB0 and Rh blood groups have been associated with various malignancies. This study aims to investigate the relationship between AB0/Rh blood groups and chondroid neoplasia.
Material and Methods : We evaluated 276 patients with chondroid neoplasia retrospectively. The blood groups and tumor localization of the patients who were operated between 2014-2019 were recorded. 129 patients who donated blood to our hospital in 2019 constituted the control group.We compared the demographic characteristics and blood groups of the patients with the control group using the chi-square test.
Results : The mean age was 52±14.6, 49±15.9, and 37±10.3 years, respectively, for enchondroma, chondrosarcoma and the control group. The tumor was mostly localized to the distal femur in both enchondroma and chondrosarcoma patients. Although the 0Rh (+) blood group rate was higher and the B (Rh (+) blood group rate was lower in patients with enchondroma and chondrosarcoma compared to the control group, this difference was not statistically significant. The A and AB blood group rates of the case and control groups were similar.
Conclusion : There was no relationship between AB0 blood groups and chondroid neoplasia. Studies investigating the relationship of different benign and malignant bone tumors with AB0 and Rh blood groups in large patient series are needed.

Anahtar Kelimeler

Enchondroma, chondrosarcoma, AB0 blood groups, malignancy

Kaynakça

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