ORAL LİKEN PLANUS: DİRENÇLİ BİR OLGUNUN TEDAVİSİ

Yıl 2014, Cilt: 48 Sayı: 1, 57 - 64, 08.04.2014

Özge Özdal Ceren Özbek Kıvanç Bektaş-kayhan Nesimi Büyükbabani Meral Ünür

Öz

Oral liken planus (OLP), oldukça yaygın görülen genellikle oral mukozanın çok katlı yassı epitel tabakasını etkileyen kronik inflamatuvar bir hastalıktır. Ortalama olarak popülasyonun %1-2'sini etkilemekle birlikte sıklıkla 3-6 dekat aralığında ve kadınlarda, erkeklere oranla 2 katı daha fazla görülmektedir. OLP'nin patogenezi tam olarak bilinmemekle birlikte, etyolojisinde immün sistemin rol oynadığı düşünülmektedir. 25 yaşındaki erkek hasta alt dudağındaki beyaz lezyonlar nedeniyle kliniğimize başvurdu. Yapılan klinik muayene sonucu dil sırtında, retromolar bölgede, dişetinde ve oral mukozanın bazı bölgelerinde de benzer lezyonlar saptandı. Direkt immunofloresan (DIF) ve histopatolojik incelemeler için biyopsi örnekleri alındı. Biyopsi sonuçlarına göre OLP teşhisi konuldu. Bu yazıdaki amacımız, hastamıza uyguladığımız tedaviyi ve tedavide gözlenen klinik değişiklikleri sunmaktır.

Anahtar Kelimeler

Oral liken planus, steroid, lezyon içi enjeksiyon

Oral Lichen Planus: Treatment of a Refractory Case

Öz

Oral lichen planus (OLP) is a relatively common, chronic inflammatory disease that often affects the stratified squamous epithelia of oral mucosa. The disease is affecting approximately 1-2% of the population. It is seen mostly in the third to sixth decades of life, and is twice as common in women than men. OLP’s pathogenesis of immune system is thought to have played a role in the etiology is not known. A 25-year-old male patient was referred our clinic due to white lesions on his lower lip. Similar lesions were detected on his tongue, retromolar region, gingiva as well as various parts of oral mucosa result of clinical examiation. Biopsies were taken for direct immunofluorescense (DIF) and histopathological examinations. As a result of bipsies OLP were diagnosed. In this paper the treatment of our patient and the clinical changes of patient with the treatment will be presented.

Anahtar Kelimeler

Oral lichen planus, steroid, intralesional injection

Kaynakça

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