INTRAOSSEOUS AND EXTRAOSSEOUS VARIANTS OF DENTINOGENIC GHOST CELL TUMOR: TWO CASE REPORTS

Yıl 2015, Cilt: 49 Sayı: 1, 56 - 60, 25.03.2015

Merva Soluk Tekkeşin , Mehmet Erdem Nedim Özer Vakur Olgaç

https://doi.org/10.17096/jiufd.38386

Öz

This paper aims to present both intraosseous and extraosseous variant of dentinogenic ghost cell tumor as well as a review of the literature. An 11-year old female patient presented a swelling and pain in the molar area of the mandible and a 15-year-old female patient reported a complaint of swelling in the right vestibular region of teeth 12 and 13(FDI 2-digit classification system). Microscopic examinations showed similar features which characterized by ameloblastoma-like islands of epithelial cells, containing numerous ghost cells. The patients have been disease-free for one year. This paper aims to describe this rare tumor and to increase the number of cases in the literature to better understand its biologic behavior and treatment options.

Anahtar Kelimeler

Dentinogenic ghost cell; intraosseous; extraosseous; odontogenic tumors

Kemik içi ve Periferik Dentinogenik Gölge Hücreli Tümör: İki olgu sunumu

Öz

Bu yazıda dentinogenik gölge hücreli tümörün kemik içi ve kemik dışı olmak üzere iki tipini sunmaktayız. Mandibula molar bölgede ağrı ve şişlik şikayeti olan 11 yaşında bir kız çocuğu ve maksilla 12- 13 numaralı dişlerin vestibül bölgesinde şişlik şikayeti olan 15 yaşında kız çocuğu kliniğe başvurmuştur. Mikroskopik değerlendirmede benzer görüntüler izlenmiştir. Epitelyal hücrelerin oluşturduğu yoğun gölge hücreleri içeren ameloblastik adacıklar görülmektedir. Bir yıllık kontrollerinde bir yineleme yoktur. Bu yazı ile ender görülen bu olguların literatüre kazandırılması ve biyolojik davranış ve tedavi seçeneklerinin daha net anlaşılması için amaçlanmıştır

Anahtar Kelimeler

Dentinogenik gölge hücreli, kemik içi, kemik dışı, odontojenik tümörler

Kaynakça

• 1. Kramer IR, Pindborg JJ, Shear M. Histological typing of odontogenic tumours. 2nd ed., Geneva: World Health Organization.1992, p 35-36.
• 2. Prætorius F, Ledesma-Montes C. Dentinogenic ghost cell tumour. Head and neck tumours, WHO classification of tumours. 5th ed., Lyon: IARC Press, 2005, p 314.
• 3. Ledesma-Montes C, Gorlin RJ, Shear M, Prae Torius F, Mosqueda-Taylor A, Altini M, Unni K, Paes de Almeida O, Carlos-Bregni R, Romero de León E, Phillips V, DelgadoAzañero W, Meneses-García A. International collaborative study on ghost cell odontogenic tumours: calcifying cystic odontogenic tumour, dentinogenic ghost cell tumour and ghost cell odontogenic carcinoma. J Oral Pathol Med 2008;37(5):302-308.
• 4. Sun G, Huang X, Hu Q, Yang X, Tang E. The diagnosis and treatment of dentinogenic ghost cell tumor. Int J Oral Maxillofac Surg 2009;38(11):1179-1183.
• 5. Li Bb, Li T. Recurrence and malignant transformation of intraosseous dentinogenic ghost cell tumor. Beijing Da Xue Xue Bao 2011;43(1):48-51.
• 6. Li BB, Gao Y. Ghost cell odontogenic carcinoma transformed from a dentinogenic ghost cell tumor of maxilla after multiple recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107(5):691-695.
• 7. Bello IO, Qannam A, Al-Zahrani A, AlDosari A. Perihepheral dentinogenic ghost cell tumor: report of a case and literatatuure review. Int J Surg Pathol 2012;20(5):494-499.
• 8. Kumar U, Vij H, Vij R, Kharbanda J, Aparna I, Radhakrishnan R. Dentinogenic ghost cell tumor of the peripheral variant mimicking epulis. Int J Dent 2010;2010:519494.
• 9. Wong YK, Chiu SC, Pang SW, Cheng JC. Peripheral dentinogenic ghost cell tumour presenting as a gingival mass. Br J Oral Maxillofac Surg 2004;42(2):173-175.
• 10. Juneja M, George J. Dentinogenic ghost cell tumor: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107(5):17-22.
• 11. Yun KI, Lee JA, Lee YS, Kim TJ, Park JU. Dentinogenic ghost cell tumors. J Oral Maxillofac Surg 2007;65(9):1816-1819.
• 12. Singhaniya SB, Barpande SR, Bhavthankar JD. Dentinogenic ghost cell tumor. J Oral Maxillofac Pathol 2009;13(2):97-100.
• 13. Kim SA, Ahn SG, Kim SG, Park JC, Lee SH, Kim J, Yoon JH. Investigation of the beta-catenin gene in a case of dentinogenic ghost cell tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(1):97-101.