Dental kök hücre kaynakları ve kemik doku mühendisliğinde kullanılma potansiyelleri

Year 2015, Volume: 49 Issue: 2, 51 - 56, 18.05.2015

Fatih Asutay , Ahmet Acar , Ümit Yolcu , Mustafa Kırtay , Hilal Alan

https://doi.org/10.17096/jiufd.42908

Abstract

Doku mühendisliği yaklaşımları, kemik
iyileşmesi ile ilgilenen her tıp alanında heyecan
uyandırmaktadır. İyileşme sürelerinin kısalması, daha
kaliteli ve fonksiyonel doku elde edilmesi ve ikincil
bir cerrahi sahaya gereksinimi ortadan kaldırması bu
yaklaşımların nihai hedeflerindendir. Mezenşimal kök
hücreler bu alandaki çalışmalarda giderek artarak
kullanılmakta ve sonuçlar umut vermektedir. Dental
kök hücreler de hem kolay temin edilebilmesi hem de
üstün özellikleri sebebiyle ön plana çıkmaktadırlar.
Bu çalışmada dental kök hücrelerin kemik doku
mühendisliği yaklaşımları için önemi ve rejenerasyon
potansiyelleri incelenmiştir.

Keywords

Dental kök hücreler, kemik dokusu mühendisliği, oral ve maksillofasiyal cerrahi

DENTAL STEM CELL SOURCES AND THEIR POTENTIALS FOR BONE TISSUE ENGINEERING

Abstract

Tissue engineering arouses excitement in all medical fields that deal with bone healing. The iyileşmesi ile ilgilenen her tıp alanında heyecan ultimate aim of these approaches are to shorten uyandırmaktadır. İyileşme sürelerinin kısalması, daha the healing process, obtain highly differentiated kaliteli ve fonksiyonel doku elde edilmesi ve ikincil functional tissues and eliminate the need for a second bir cerrahi sahaya gereksinimi ortadan kaldırması bu surgical site required for autogenous bone grafts. Mesenchymal stem cells have been increasingly hücreler bu alandaki çalışmalarda giderek artarak used in the experiments which were conducted in kullanılmakta ve sonuçlar umut vermektedir. Dental these fields and the results are promising. Dental stem cells have come to the forefront both because of their relative ease of access and also their Bu çalışmada dental kök hücrelerin kemik doku superior characteristics. This article investigates mühendisliği yaklaşımları için önemi ve rejenerasyon the importance of dental stem cells for bone tissue engineering and their regeneration potentials

Keywords

Dental stem cells, bone tissue engineering, oral and maxillofacial surgery

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