Theoretical Study of Quercetin Derivatives

Ramazan Erenler; Faik Gokalp

EN

Theoretical Study of Quercetin Derivatives

Abstract

Kuesetin, birçok bitkiden izole edilen, çok sayıda biyolojik aktivite gösteren önemli bir doğal üründür. Doğal ürünler, formakolojik etkilerini güçlendirmek için foksiyonel hale getirilir. Bundan dolayı, en aktif bileşiği ortaya koymak için, kuersetin türevlendirilerek teorik hesaplamalar yapıldı. Ayrıca, bu çalışma aktif ve hedef bileşiklerin sentezi için sentetik kimyacılara ilham verecektir. Kuersetin türevlerinin kimyasal özellikleri teorik olarak araştırıldı. Bileşiklerin kuantum hesaplamaları, B3lyp/6-31+g(d,p) metoduyla yapıldı. Bileşik 6 en kararlı bileşik olarak belirlendi. İnstenilen reaksiyonlar için ve vucudaki dokuya ulaşması bakımından bu bileşik diğerlerine nazaran daha üstündür. Bileşik 3’ün yüksek polaritesinden dolayı, kanda çözünebilme ve farmasötik endüstrisinde kullanılabilme potansiyeli vardır.

Keywords

Quercetin,theoretical calculation,flavonoid

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Ramazan Erenler ^*
0000-0002-0505-3190
Türkiye

Faik Gokalp
0000-0003-4363-3839
Türkiye

Publication Date

December 15, 2019

Submission Date

April 15, 2019

Acceptance Date

September 25, 2019

Published in Issue

Year 2019 Volume: 8 Number: 1

IZ

https://izlik.org/JA24XD46KT

APA

Erenler, R., & Gokalp, F. (2019). Theoretical Study of Quercetin Derivatives. Journal of New Results in Science, 8(1), 1-5. https://izlik.org/JA24XD46KT

AMA

1.Erenler R, Gokalp F. Theoretical Study of Quercetin Derivatives. JNRS. 2019;8(1):1-5. https://izlik.org/JA24XD46KT

Chicago

Erenler, Ramazan, and Faik Gokalp. 2019. “Theoretical Study of Quercetin Derivatives”. Journal of New Results in Science 8 (1): 1-5. https://izlik.org/JA24XD46KT.

EndNote

Erenler R, Gokalp F (December 1, 2019) Theoretical Study of Quercetin Derivatives. Journal of New Results in Science 8 1 1–5.

IEEE

[1]R. Erenler and F. Gokalp, “Theoretical Study of Quercetin Derivatives”, JNRS, vol. 8, no. 1, pp. 1–5, Dec. 2019, [Online]. Available: https://izlik.org/JA24XD46KT

ISNAD

Erenler, Ramazan - Gokalp, Faik. “Theoretical Study of Quercetin Derivatives”. Journal of New Results in Science 8/1 (December 1, 2019): 1-5. https://izlik.org/JA24XD46KT.

JAMA

1.Erenler R, Gokalp F. Theoretical Study of Quercetin Derivatives. JNRS. 2019;8:1–5.

MLA

Erenler, Ramazan, and Faik Gokalp. “Theoretical Study of Quercetin Derivatives”. Journal of New Results in Science, vol. 8, no. 1, Dec. 2019, pp. 1-5, https://izlik.org/JA24XD46KT.

Vancouver

1.Ramazan Erenler, Faik Gokalp. Theoretical Study of Quercetin Derivatives. JNRS [Internet]. 2019 Dec. 1;8(1):1-5. Available from: https://izlik.org/JA24XD46KT