Research Article

Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women

Volume: 5 Number: 5 October 26, 2024
TR EN

Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women

Abstract

Aims: This study aims to analyze the treatment approaches and reproductive outcomes of women diagnosed with cesarean scar pregnancy (CSP). Methods: A retrospective analysis was conducted on sixty patients diagnosed with CSP between January 2020 and December 2023 at two tertiary centers with a combined total of 49,733 births during the study period. Demographic, clinical, and laboratory characteristics, complications, treatment methods, and reproductive outcomes were examined. Patients were categorized into two groups based on their treatment approach: isolated treatment (n=45, 75%) and combined treatment (n=15, 25%), and the outcomes of the two groups were compared. Results: The mean age of all patients was 34 years (±5.5) (range: 21-46). The mean gestational age at admission was 6.86 weeks (±1.82), with 35% showing positive fetal heartbeats. Complications occurred in 28.3% of cases, with hematomas being the most common (26.7%). The combined treatment group had higher rates of blood transfusions and complications, including hematomas and bladder injuries (p=0.005 and p<0.001, respectively). Of the 16 patients (26.7%) who desired future pregnancy, 14 successfully conceived. Among these pregnancies, 7 resulted in early pregnancy loss, while 7 resulted in live births, all of which were delivered after 35 weeks of gestation. Conclusion: Early diagnosis and evidence-based treatment of CSP are essential for preventing life-threatening obstetric complications. Larger, prospective studies are required to establish optimal diagnostic and treatment strategies.

Keywords

Supporting Institution

Financial Disclosure: The authors declared that this study has received no financial support.

Ethical Statement

Ethics Committee Approval: The study was initiated with the approval of the Ankara Etlik City Hospital Ethics Committee (Approval No. AESH-EK1-2023-683 ).

Thanks

Acknowledgment: The authors extend their sincere admiration and appreciation to Prof. Dr. Can Tekin Iskender, whose profound expertise and experience significantly advanced our scientific progress and passed away so early.

References

  1. Lai YM, Lee JD, Lee CL, Chen TC, Soong YK. An ectopic pregnancy embedded in the myometrium of a previous cesarean section scar. Acta Obstet Gynecol Scan. Published online January 1, 1995. Accessed February 23, 2024. https://www.tandfonline.com/ doi/abs/10.3109/00016349509024394
  2. Timor-Tritsch IE, Monteagudo A. Unforeseen consequences of the increasing rate of cesarean deliveries: early placenta accreta and cesarean scar pregnancy. A review. Am J Obstet Gynecol. 2012;207 (1):14-29. doi:10.1016/j.ajog.2012.03.007
  3. Huo S, Shen L, Ju Y, Liu K, Liu W. Treatments for cesarean scar pregnancy: 11-year experience at a medical center. J Matern Fetal Neonatal Med. 2023;36(1):2162818. doi:10.1080/14767058.2022.2162818
  4. Seow KM, Huang LW, Lin YH, Yan-Sheng Lin M, Tsai YL, Hwang JL. Cesarean scar pregnancy: issues in management. Ultrasound Obstet Gynecol. 2004;23(3):247-253. doi:10.1002/uog.974
  5. Jaunıaux E, Burton GJ. Pathophysiology of placenta accreta spectrum disorders: a review of current findings. Clin Obstet Gynecol. 2018;61(4):743-754. doi:10.1097/GRF.0000000000000392
  6. Tantbirojn P, Crum CP, Parast MM. Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast. Placenta. 2008;29(7):639-645. doi:10.1016/j.placenta.2008.04.008
  7. Jauniaux E, Hussein AM, Elbarmelgy RM, Elbarmelgy RA, Burton GJ. Failure of placental detachment in accreta placentation is associated with excessive fibrinoid deposition at the utero-placental interface. Am J Obstet Gynecol. 2022;226(2):243.e1-243.e10. doi:10.1016/j.ajog.2021.08.026
  8. Timor-Tritsch IE, Monteagudo A, Cali G, et al. Cesarean scar pregnancy is a precursor of morbidly adherent placenta. Ultrasound Obstet Gynecol. 2014;44(3):346-353. doi:10.1002/uog.13426

Details

Primary Language

English

Subjects

Obstetrics and Gynaecology

Journal Section

Research Article

Publication Date

October 26, 2024

Submission Date

September 15, 2024

Acceptance Date

October 1, 2024

Published in Issue

Year 2024 Volume: 5 Number: 5

APA
Şeyhanlı, Z., Bayraktar, B., Karabay, G., Bucak, M., Vanlı Tonyalı, N., Aktemur, G., Tokgöz, B., Demir Çendek, B., Çelen, Ş., Çağlar, A., & Üstün, Y. (2024). Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women. Journal of Medicine and Palliative Care, 5(5), 256-264. https://doi.org/10.47582/jompac.1550289
AMA
1.Şeyhanlı Z, Bayraktar B, Karabay G, et al. Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women. J Med Palliat Care / JOMPAC / jompac. 2024;5(5):256-264. doi:10.47582/jompac.1550289
Chicago
Şeyhanlı, Zeynep, Burak Bayraktar, Gülşan Karabay, et al. 2024. “Management and Reproductive Outcomes Following Cesarean Scar Pregnancy: Experiences of Two Tertiary Centers in a Cohort of 60 Women”. Journal of Medicine and Palliative Care 5 (5): 256-64. https://doi.org/10.47582/jompac.1550289.
EndNote
Şeyhanlı Z, Bayraktar B, Karabay G, Bucak M, Vanlı Tonyalı N, Aktemur G, Tokgöz B, Demir Çendek B, Çelen Ş, Çağlar A, Üstün Y (October 1, 2024) Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women. Journal of Medicine and Palliative Care 5 5 256–264.
IEEE
[1]Z. Şeyhanlı et al., “Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women”, J Med Palliat Care / JOMPAC / jompac, vol. 5, no. 5, pp. 256–264, Oct. 2024, doi: 10.47582/jompac.1550289.
ISNAD
Şeyhanlı, Zeynep - Bayraktar, Burak - Karabay, Gülşan - Bucak, Mevlüt - Vanlı Tonyalı, Nazan - Aktemur, Gizem - Tokgöz, Betül et al. “Management and Reproductive Outcomes Following Cesarean Scar Pregnancy: Experiences of Two Tertiary Centers in a Cohort of 60 Women”. Journal of Medicine and Palliative Care 5/5 (October 1, 2024): 256-264. https://doi.org/10.47582/jompac.1550289.
JAMA
1.Şeyhanlı Z, Bayraktar B, Karabay G, Bucak M, Vanlı Tonyalı N, Aktemur G, Tokgöz B, Demir Çendek B, Çelen Ş, Çağlar A, Üstün Y. Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women. J Med Palliat Care / JOMPAC / jompac. 2024;5:256–264.
MLA
Şeyhanlı, Zeynep, et al. “Management and Reproductive Outcomes Following Cesarean Scar Pregnancy: Experiences of Two Tertiary Centers in a Cohort of 60 Women”. Journal of Medicine and Palliative Care, vol. 5, no. 5, Oct. 2024, pp. 256-64, doi:10.47582/jompac.1550289.
Vancouver
1.Zeynep Şeyhanlı, Burak Bayraktar, Gülşan Karabay, Mevlüt Bucak, Nazan Vanlı Tonyalı, Gizem Aktemur, Betül Tokgöz, Büşra Demir Çendek, Şevki Çelen, Ali Çağlar, Yaprak Üstün. Management and reproductive outcomes following cesarean scar pregnancy: experiences of two tertiary centers in a cohort of 60 women. J Med Palliat Care / JOMPAC / jompac. 2024 Oct. 1;5(5):256-64. doi:10.47582/jompac.1550289

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