Erektil disfonksiyonu olan hastalarda ventriküler repolarizasyon parametrelerinin değerlendirilmesi

Abstract

Amaç; Erektil disfonksiyon (ED), orta yaşlı ve yaşlı erkekleri etkileyen vaskülojenik bir hastalıktır. ED, gelecekteki kardiyovasküler hastalıkların (KVD) iyi bir öngörücüsü olarak kabul edilir. Ayrıca, EKG'deki ventriküler repolarizasyon parametrelerinin çeşitli hastalıklar için artmış ventriküler aritmogenezi ve ani ölümle ilişkili olduğunu gösteren çalışmalar da vardır. Bu çalışmada, ED ile Tp-e/QTc oranı, Tp-e/QT oranı ve Tp-e aralığı arasındaki ilişki araştırılacaktır. Yöntemler: Çalışmaya hastanemizin üroloji kliniğine başvuran vasküler ED tanısı almış 87 hasta dahil edildi. Tp-e aralığı, T dalgasının tepe noktası ile T dalgasının sonu arasındaki mesafe olarak tanımlandı. Bulgular: Tp-e aralığı, Tp-e/QT oranı ve Tp-e/QTc oranı, ED hastalarında kontrol grubuna kıyasla istatistiksel olarak anlamlı derecede yüksekti (genel p <0.01). Korelasyon analizimiz, ED'li hastalarda IIEF-5 skoru ile Tp-e aralığı, Tp-e/QT oranı ve Tp-e/QTc oranı arasında anlamlı negatif korelasyonlar buldu (sırasıyla r=-0,714, p<0,001; r=-0,729, p<0,001, r=-0,776, p<0,001). Sonuç: EKG'de ölümcül ventriküler aritmiler için önemli olduğu düşünülen Tp-e aralığı, Tp-e/QT oranı ve Tp-e/QTc oranının ED hastalarında anlamlı şekilde daha uzun olduğunu bulduk.

Keywords

• Seksüel fonksiyon
• Tp-e aralığı
• Tp-e/QT oranı
• Tp-e/QTc oranı

Evaluation of ventricular repolarization parameters in patients with erectile dysfunction

Abstract

Aims: Erectile dysfunction (ED) is recognized as a good predictor of future cardiovascular disease (CVD). There are also studies showing that ventricular repolarization parameters on Electrocardiography (ECG) are associated with increased ventricular arrhythmogenesis and sudden death for various diseases. In this study, we will investigate the relationship between ED and Tp-e to QTc ratio, Tp-e interval/QT interval (Tp-e/QT) ratio and Tp-e interval. Methods: The study included 87 patients admitted to the urology clinic of our hospital and diagnosed with vascular ED. The distance between the peak of the T wave and the end of the T wave was defined as the Tp-e interval. QT interval was defined as the interval from the beginning of the QRS complex to the end of the T wave and adjusted according to heart rate (QTc, Bazett formula). Results: Tp-e-QTc ratio, Tp-e-QT ratio and Tp-e interval were statistically and significantly higher in patients with ED compared to the control group (overall p<0.01). Our correlation analysis found significant negative correlations between IIEF-5 score and Tp-e-QTc ratio, Tp-e-QT ratio and Tp-e interval in patients with ED (r=-0.714, p<0.001; r=-0.729, p<0.001, r=-0.776, p<0.001, respectively). Conclusion: We found that Tp-e/QTc ratio, Tp-e/QT ratio and Tp-e interval, which are considered to be important for fatal ventricular arrhythmias on ECG, were significantly longer in emergency department patients.

Keywords

• Sexual function
• Tp-e to QTc ratio
• Tp-e to QT ratio and Tp-e interval

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