A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients

Mehmet Sait Şimşek; Kağan Fatih Kuşan; Arzu Özdemir; Şevval Uran

A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients

Abstract

Aims: This study aimed to evaluate the seroprevalence of HBV, HCV, and HIV in patients undergoing oral surgery and to assess concordance between patient self-reports and serological results. Additionally, occupational distribution, dental attendance, and family history of seropositive patients were analyzed. Methods: As part of the institutional infection control protocol, all patients scheduled for invasive oral surgical procedures under local anesthesia routinely underwent preoperative serological screening. This retrospective study included 3968 patients who underwent oral surgical procedures at the Department of Oral and Maxillofacial Surgery at Adıyaman University between March 2025 and March 2026. Preoperative blood test results, including HBsAg, anti-HCV, and anti-HIV, were retrospectively retrieved from archived laboratory records. Concordance between patient self-reported medical history and serological findings was evaluated. In seropositive patients, occupational status, dental attendance, and family history of HBV, HCV, or HIV infection were also analyzed. Results: A total of 3968 patients were included (41.2% male, 58.8% female). HBsAg, anti-HCV, and anti-HIV positivity rates were 0.96%, 0.20%, and 0.05%, respectively, with a co-infection rate of 0.05%. Concordance between patient-reported history and serological findings was assessed, and occupational status, dental attendance, and family history were evaluated among seropositive patients. Conclusion: While seroprevalence rates were comparable to the general population, incomplete concordance between selfreported history and serological findings highlights the importance of preoperative screening and strict infection control.

Keywords

References

Zoulim F, Perrillo R. Hepatitis B: reflections on the current approach to antiviral therapy. J Hepatol. 2008;48(Suppl 1):S2-S19. doi:10.1016/j.jhep.2008.01.011
Dong Y, Qiu C, Xia X, et al. Hepatitis B virus and hepatitis C virus infection among HIV-1-infected injection drug users in Dali, China: prevalence and infection status in a cross-sectional study. Arch Virol. 2015;160(4):929-936. doi:10.1007/s00705-014-2311-0
Boşnak VK, Karaoğlan İ, Namıduru M, Şahin A. Gaziantep Üniversitesi Şahinbey Araştırma ve Uygulama Hastanesi sağlık çalışanlarında hepatit B, hepatit C ve HIV seroprevalansı. Viral Hepatit Derg. 2013; 19(1):11-14. doi:10.4274/Vhd.69188
Baysal B, Kaya Ş. Bir eğitim araştırma hastanesi personelinde HBV, HCV ve HIV seroprevalansı. Viral Hepatit Derg. 2012;18(3):94-97. doi:10.4274/Vhd.43531
Arıcan G, Uğurlu H, Küçük B, Aral M, Muratdağı G. Kahramanmaraş Sütçü İmam Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi çalışanlarında hepatit B ve C enfeksiyonu seropozitifliğinin araştırılması. Sakarya Med J. 2019;9(4):592-596. doi:10.31832/smj.559018
Tekin A, Deveci Ö. Bir devlet hastanesi çalışanlarında HBV, HCV ve HIV seroprevalansı. J Clin Exp Invest. 2010;1(2):99-103. doi:10.5799/ahinjs.01.2010.02.0020
Schillie S, Vellozzi C, Reingold A, et al. Prevention of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2018; 67(1):1-31. doi:10.15585/mmwr.rr6701a1
Tang LSY, Covert E, Wilson E, Kottilil S. Chronic hepatitis B infection: a review. JAMA. 2018;319(17):1802-1813. doi:10.1001/jama.2018.3795

Ibrahim NK, Alwafi HA, Sangoof SO, Turkistani AK, Alattas BM. Cross-infection and infection control in dentistry: knowledge, attitude and practice of patients attending dental clinics in King Abdulaziz University Hospital, Jeddah, Saudi Arabia. J Infect Public Health. 2017; 10(4):438-445. doi:10.1016/j.jiph.2016.06.002
Schmalz G, Brauer L, Haak R, Ziebolz D. Evaluation of a concept to classify anamnesis-related risk of complications and oral diseases in patients attending the clinical course in dental education. BMC Oral Health. 2023;23(1):609. doi:10.1186/s12903-023-03343-x
Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev. 2006;28:112-125. doi:10.1093/epirev/mxj009
Beltrami EM, Williams IT, Shapiro CN, Chamberland ME. Risk and management of blood-borne infections in health care workers. Clin Microbiol Rev. 2000;13(3):385-407. doi:10.1128/CMR.13.3.385-407.2000
Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology. 2009;50(3):661-662. doi:10.1002/hep.23190
Ege B, Küçük AO, Koparal M. Investigation of preoperative seroprevalence of HBsAg, anti-HBs, anti-HCV, anti-HIV and vaccination level of patients undergoing dental surgical procedures under local anesthesia. Ann Med Res. 2019;26(8):1503-1507. doi:10.5455/annalsmedres.2019.04.208
Uzun B, Güngör S, Demirci M. Seroprevalence of transfusion transmissible infections among blood donors in western part of Turkey: a six-year study. Transfus Apher Sci. 2013;49(3):511-515. doi:10.1016/j.transci.2013.02.039
Dilek İ, Demir C, Bay A, Akdeniz H, Öner AF. Seropositivity rates of HBsAg, anti-HCV, anti-HIV and VDRL in blood donors in Eastern Turkey. Turk J Haematol. 2007;24(1):4-7.
Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology. 2013;57(4):1333-1342. doi:10.1002/hep.26141
Tozun N, Ozdogan O, Cakaloglu Y, et al. Seroprevalence of hepatitis B and C virus infections and risk factors in Turkey: a fieldwork TURHEP study. Clin Microbiol Infect. 2015;21(11):1020-1026. doi:10.1016/j.cmi.2015.06.028
Yıldırım M, Çakır S, Geyik MF, Özdemir D, Güçlü E, Çakır M. Seroprevalences and associated risk factors of hepatitis B and C in adults. Turk J Med Sci. 2014;44(5):824-831. doi:10.3906/sag-1309-25
Badshah Y, Shabbir M, Khan K, et al. HCV and HBV genotypes: vital in the progression of HCV/HBV co-infection. BMC Gastroenterol. 2025; 25(1):6. doi:10.1186/s12876-025-03587-7
Shaghaghian S, Homayooni M, Amin M, Rezazadeh F. Oral health status of patients infected with human immunodeficiency virus and related factors, Iran: a cross-sectional study. BMC Oral Health. 2021;21(1):657. doi:10.1186/s12903-021-02002-3
Alter MJ. Epidemiology of viral hepatitis and HIV co-infection. J Hepatol. 2006;44(1 Suppl):S6-S9. doi:10.1016/j.jhep.2005.11.004
Polaris Observatory Collaborators. Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study. Lancet Gastroenterol Hepatol. 2018;3(6):383-403. doi:10.1016/S2468-1253(18)30056-6
Karichashvili L, Shadaker S, Schumacher IT, et al. Assessing the seroprevalence of and knowledge, attitudes and practices related to hepatitis B and hepatitis C among dental health professionals in the country of Georgia, 2023. J Viral Hepat. 2026;33(2):e70126. doi:10.1111/jvh.70126
Diel R, Nienhaus A. Risk of hepatitis B transmission by healthcare workers: a systematic review. GMS Hyg Infect Control. 2025;20:Doc43. doi:10.3205/dgkh000572
Conners EE, Panagiotakopoulos L, Hofmeister MG, et al. Screening and testing for hepatitis B virus infection: CDC recommendations—United States, 2023. MMWR Recomm Rep. 2023;72(1):1-25. doi:10.15585/mmwr.rr7201a1
Madhavan A, Sachu A, Balakrishnan AK, Balakrishnan S, Vasudevapanicker J. Prevalence of anti-HBc antibodies among HBsAg-negative individuals and its association with occult hepatitis B. J Lab Physicians. 2021;13(1):1-5. doi:10.1055/s-0041-1723046
Summa KC, Maddur H. Hepatitis C antibody positive, RNA negative. Clin Liver Dis (Hoboken). 2019;14(1):5-7. doi:10.1002/cld.755
Dighe K, Colak O, Moitra P, et al. Distinguishing active HIV-1 infection from vaccine-induced seropositivity in HIV vaccine trial participants. Sci Adv. 2025;11(49):eadz5639. doi:10.1126/sciadv.adz5639

Details

Primary Language

English

Subjects

Oral and Maxillofacial Surgery

Journal Section

Research Article

Authors

Mehmet Sait Şimşek
0009-0003-4177-140X
Türkiye

Kağan Fatih Kuşan ^*
0009-0007-0080-8703
Türkiye

Arzu Özdemir
0009-0004-4324-765X
Türkiye

Şevval Uran
0009-0009-6819-0190
Türkiye

Publication Date

August 15, 2026

Submission Date

April 29, 2026

Acceptance Date

July 20, 2026

Published in Issue

Year 2026 Volume: 7 Number: 4

IZ

https://izlik.org/JA36YM95XG

Cite

RIS / Bibtex

APA

Şimşek, M. S., Kuşan, K. F., Özdemir, A., & Uran, Ş. (2026). A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients. Journal of Medicine and Palliative Care, 7(4), 777-782. https://izlik.org/JA36YM95XG

AMA

1.Şimşek MS, Kuşan KF, Özdemir A, Uran Ş. A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients. J Med Palliat Care / JOMPAC / jompac. 2026;7(4):777-782. https://izlik.org/JA36YM95XG

Chicago

Şimşek, Mehmet Sait, Kağan Fatih Kuşan, Arzu Özdemir, and Şevval Uran. 2026. “A Retrospective Assessment of HIV, HBV, and HCV Seroprevalence and Concordance Between Patient Self-Reported Status and Serological Findings in Oral Surgery Patients”. Journal of Medicine and Palliative Care 7 (4): 777-82. https://izlik.org/JA36YM95XG.

EndNote

Şimşek MS, Kuşan KF, Özdemir A, Uran Ş (August 1, 2026) A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients. Journal of Medicine and Palliative Care 7 4 777–782.

IEEE

[1]M. S. Şimşek, K. F. Kuşan, A. Özdemir, and Ş. Uran, “A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients”, J Med Palliat Care / JOMPAC / jompac, vol. 7, no. 4, pp. 777–782, Aug. 2026, [Online]. Available: https://izlik.org/JA36YM95XG

ISNAD

Şimşek, Mehmet Sait - Kuşan, Kağan Fatih - Özdemir, Arzu - Uran, Şevval. “A Retrospective Assessment of HIV, HBV, and HCV Seroprevalence and Concordance Between Patient Self-Reported Status and Serological Findings in Oral Surgery Patients”. Journal of Medicine and Palliative Care 7/4 (August 1, 2026): 777-782. https://izlik.org/JA36YM95XG.

JAMA

1.Şimşek MS, Kuşan KF, Özdemir A, Uran Ş. A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients. J Med Palliat Care / JOMPAC / jompac. 2026;7:777–782.

MLA

Şimşek, Mehmet Sait, et al. “A Retrospective Assessment of HIV, HBV, and HCV Seroprevalence and Concordance Between Patient Self-Reported Status and Serological Findings in Oral Surgery Patients”. Journal of Medicine and Palliative Care, vol. 7, no. 4, Aug. 2026, pp. 777-82, https://izlik.org/JA36YM95XG.

Vancouver

1.Mehmet Sait Şimşek, Kağan Fatih Kuşan, Arzu Özdemir, Şevval Uran. A retrospective assessment of HIV, HBV, and HCV seroprevalence and concordance between patient self-reported status and serological findings in oral surgery patients. J Med Palliat Care / JOMPAC / jompac [Internet]. 2026 Aug. 1;7(4):777-82. Available from: https://izlik.org/JA36YM95XG