Case Report

A rare presentation of Graves’ disease: bilateral pitting edema of the legs

Volume: 2 Number: 3 September 8, 2021
EN TR

A rare presentation of Graves’ disease: bilateral pitting edema of the legs

Abstract

Graves’ disease has many extrathyroidal manifestations. In the literature, bilateral pretibial pitting edema in hyperthyroidism cases has been reported in a few case reports. In the current presentation, we report a case of Graves who had leg and hand swelling for two weeks and whose findings regressed rapidly with treatment. Diffuse, bilateral pitting pretibial edema, which may occur due to many etiologies, should also be considered in the differential diagnosis of hyperthyroidism.

Keywords

References

  1. Ai J, Leonhardt JM, Heymann WR. Autoimmune thyroid diseases: etiology, pathogenesis, and dermatologic manifestations. J Am Acad Dermatol 2003; 48: 641-59.
  2. Schwartz KM, Fatourechi V, Ahmed DD, Pond GR. Dermopathy of Graves’ disease (pretibial myxedema): long-term outcome. J Clin Endocrinol Metab 2002; 87: 438-46.
  3. Chajek T, Romanoff H. Cushing syndrome with cyclical edema and periodic secretion of corticosteroids. Arch Intern Med 1976; 136: 441-3.
  4. Mahajan SK, Machhan PC, Sood, BR, et al. Pitting edema in hypothyroidism. J Assoc Physicians India 2003; 51: 885.
  5. Hataya Y, Akamizu T, Kanamoto N, Moriyama K, Shimatsu A, Nakao K. A case of subclinical hypothyroidism developing marked pleural effusions and peripheral edema with elevated vascular endothelial growth factor. Endocr J 2007; 54: 577-84.
  6. Osuna PM, Udovcic M, Sharma MD. Hyperthyroidism and the Heart. Methodist Debakey c-Cardiovasc J 2017; 13: 60-3.
  7. Chapman EM, Maloof F. Bizarre clinical manifestations of hyperthyroidism. N Engl J Med 1956; 254: 1–5.
  8. Toft JC, Larsen S. Tendency to edema as the initial symptom of hyperthyroidism. Ugeskr Laeger 1992; 154: 90-1.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Case Report

Publication Date

September 8, 2021

Submission Date

December 11, 2020

Acceptance Date

March 4, 2021

Published in Issue

Year 2021 Volume: 2 Number: 3

APA
Bostan, H., Ucan, B., Kizilgul, M., Düğer, H., Akhanlı, P., & Çakal, E. (2021). A rare presentation of Graves’ disease: bilateral pitting edema of the legs. Journal of Medicine and Palliative Care, 2(3), 95-97. https://doi.org/10.47582/jompac.839026
AMA
1.Bostan H, Ucan B, Kizilgul M, Düğer H, Akhanlı P, Çakal E. A rare presentation of Graves’ disease: bilateral pitting edema of the legs. J Med Palliat Care / JOMPAC / jompac. 2021;2(3):95-97. doi:10.47582/jompac.839026
Chicago
Bostan, Hayri, Bekir Ucan, Muhammed Kizilgul, Hakan Düğer, Pınar Akhanlı, and Erman Çakal. 2021. “A Rare Presentation of Graves’ Disease: Bilateral Pitting Edema of the Legs”. Journal of Medicine and Palliative Care 2 (3): 95-97. https://doi.org/10.47582/jompac.839026.
EndNote
Bostan H, Ucan B, Kizilgul M, Düğer H, Akhanlı P, Çakal E (September 1, 2021) A rare presentation of Graves’ disease: bilateral pitting edema of the legs. Journal of Medicine and Palliative Care 2 3 95–97.
IEEE
[1]H. Bostan, B. Ucan, M. Kizilgul, H. Düğer, P. Akhanlı, and E. Çakal, “A rare presentation of Graves’ disease: bilateral pitting edema of the legs”, J Med Palliat Care / JOMPAC / jompac, vol. 2, no. 3, pp. 95–97, Sept. 2021, doi: 10.47582/jompac.839026.
ISNAD
Bostan, Hayri - Ucan, Bekir - Kizilgul, Muhammed - Düğer, Hakan - Akhanlı, Pınar - Çakal, Erman. “A Rare Presentation of Graves’ Disease: Bilateral Pitting Edema of the Legs”. Journal of Medicine and Palliative Care 2/3 (September 1, 2021): 95-97. https://doi.org/10.47582/jompac.839026.
JAMA
1.Bostan H, Ucan B, Kizilgul M, Düğer H, Akhanlı P, Çakal E. A rare presentation of Graves’ disease: bilateral pitting edema of the legs. J Med Palliat Care / JOMPAC / jompac. 2021;2:95–97.
MLA
Bostan, Hayri, et al. “A Rare Presentation of Graves’ Disease: Bilateral Pitting Edema of the Legs”. Journal of Medicine and Palliative Care, vol. 2, no. 3, Sept. 2021, pp. 95-97, doi:10.47582/jompac.839026.
Vancouver
1.Hayri Bostan, Bekir Ucan, Muhammed Kizilgul, Hakan Düğer, Pınar Akhanlı, Erman Çakal. A rare presentation of Graves’ disease: bilateral pitting edema of the legs. J Med Palliat Care / JOMPAC / jompac. 2021 Sep. 1;2(3):95-7. doi:10.47582/jompac.839026

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