Postoperative results and the effects of extended partial laryngectomy on the quality of life

Abstract

Background/Aim: Larynx cancers account for 2-5% of all malignancies worldwide. With early diagnosis, radiotherapy or a partial laryngectomy may help preserve voice and laryngeal functions and reduce morbidity. This study aimed to evaluate how laryngeal functions, voice, and life quality were affected in larynx cancer patients after partial and extended partial laryngectomy. Methods: The patients who were diagnosed with larynx cancer and underwent partial (supraglottic laryngectomy (SGL), supracricoid laryngectomy (SCL)) or extended partial laryngectomy (extended supraglottic laryngectomy (ESGL) and extended supracricoid laryngectomy (ESCL)) between May 2010 and December 2015 in the otorhinolaryngology clinic of a Training and Research Hospital were included in this study. A questionnaire comprising three forms was filled in by these patients. Voice quality, duration of hospitalization, time until removal of the nasogastric tube, location of the tumor, time of decannulation, swallowing, and cough were compared with regards to the types of laryngectomies. Results: Our study began with 102 patients who had a partial laryngectomy; however, twelve who eventually had to undergo a total laryngectomy were excluded. Of the remaining 90 patients, 67 filled out our questionnaire. Functional score (FS), social functional score (SFS), symptom score (SS), fatigue score (FAS), general health score (GHS), and swallowing symptoms score (HNSW) were calculated and compared. These scores did not differ with the types of laryngectomies. In terms of voice quality, there were significant differences between ESCL-SGL, SCL-SGL, ESGL-SGL groups (P=0.001, P=0.004, and P=0.004, respectively). Conclusion: Despite numerous changes in swallowing physiology and larynx anatomy after partial and extended partial laryngectomy, swallowing function is restored, and the patients can lead a healthy life.

Keywords

• Larynx cancer
• Life quality
• Voice

Genişletilmiş Parsiyel Larenjektomili Hastalarda Postoperatif Bulgular Ve Yaşam Kalitesi Üzerine Etkisi

Öz

Amaç: Larenks kanseri nedeniyle parsiyel larenjektomi ve genişletilmiş parsiyel larenjektomi olan hastaların larengeal fonksiyonların ne kadar etkilendiği, hastaların ses kalitesinin son durumu, hastaların larenjektomiden sonraki dönemdeki hayat kalitesi değerlendirildi. Yöntemler: Araştırma ve Uygulama Hastanesi Kulak Burun Boğaz Kliniği’nde Mayıs 2010 ile Aralık 2015 tarihleri arasında larenks kanseri tanısı almış parsiyel larenjektomi ve genişletilmiş parsiyel larenjektomi yapılmış hastalar dahil edildi. Bu hastalara 3 formdan oluşan anket formları doldurtuldu. Bulgular: Çalışmamıza 102 parsiyel larenjektomi yapılan hasta ile başlandı. Bu hastalardan 12’si takiplerde total larenjektomiye çevirildi ve bu hastalar listeden çıkarıldı. Kalan 90 hastadan 67’si anketimize katıldı. Hastaların ses kalitesi, hastanede kalış süresi, nasogastrik çekme süresi, tümörün yerleşim yeri, dekanülasyon süresi, gıdalarla öksürük ilişkisi larenjektomi tiplerine göre değerlendirildi. Sonuç: Larenjektomi tiplerine göre fonksiyonel skoru (FS), sosyal fonksiyon skoru (SFK), semptom skoru (SS), yorgunluk skoru (FAS), genel sağlık skoru (GHS) ve yutma semptom skoru (HNSW) hesaplanarak karşılaştırma yapıldı. Bu karşılaştırmalarda istatistiksel olarak anlamlı fark bulunamadı. Ses kalitesi açısından GSCL-SGL, SCL-SGL, GSGL-SGL grupları arasında anlamlı fark vardı (sırasıyla p=0,001, p=0,004, p=0,004).

Anahtar Kelimeler

• Larenks kanseri
• yaşam kalitesi
• ses

Kaynakça

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