Review

Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications

Volume: 11 Number: 4 December 3, 2024
EN

Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications

Abstract

This review explores the innovative use of nano-catalysts in the synthesis of 5-substituted 1H-tetrazole derivatives, highlighting their significant biological applications. The novel methodologies discussed demonstrate enhanced efficiency and selectivity in the production of these compounds. Key findings include the optimization of reaction conditions and the discovery of new catalytic pathways that improve yield and reduce reaction time. The synthesized tetrazole derivatives exhibit strong potential as therapeutic agents due to their biological activity. This work provides a comprehensive overview of the state-of-the-art techniques in nano-catalytic synthesis, emphasizing their practical applications in medicinal chemistry and materials science.

Keywords

Ethical Statement

Ethical approval was not required, as the study conducted did not involve any ethical concerns or issues.

References

  1. 1. Butler RN, Fox A, Collier S, Burke LA. Pentazole chemistry: The mechanism of the reaction of aryldiazonium chlorides with azide ion at −80 °C: Concerted versus stepwise formation of arylpentazoles, detection of a pentazene intermediate, a combined 1H and 15N NMR experimental and ab initio theoretical study. J Chem Soc Perkin Trans 2 [Internet]. 1998 Jan 1;1998(10):2243–8. Available from: .
  2. 2. Jursic BS, Leblanc BW. Preparation of tetrazoles from organic nitriles and sodium azide in micellar media. J Heterocycl Chem [Internet]. 1998 Mar 11;35(2):405–8. Available from: .
  3. 3. Izsák D, Klapötke TM, Lutter FH, Pflüger C. Tailoring the energetic properties of 5‐(5‐Amino‐1,2,3‐triazol‐4‐yl)tetraz­ole and ts derivatives by salt formation: from sensitive primary to insensitive secondary explosives. Eur J Inorg Chem [Internet]. 2016 Apr 18;2016(11):1720–9. Available from: .
  4. 4. Singh H, Singh Chawla A, Kapoor VK, Paul D, Malhotra RK. Medicinal chemistry of tetrazoles. In: Progress in Medicinal Chemistry [Internet]. Elsevier; 1980. p. 151–83. Available from: .
  5. 5. Okabayashi T, Kano H, Makisumi Y. Action of substituted azaindolizines on microorganisms. I. action on lactic acid bacteria. Chem Pharm Bull [Internet]. 1960 Feb 25;8(2):157–62. Available from: .
  6. 6. Sangal SK, Kumar A. Synthesis of some new antifungal tetrazolyl sulfides. J. Ind. Chem. Soc. 1986; 63; 351–3.
  7. 7. Witkowski JT, Robins RK, Sidwell RW, Simon LN. Design, synthesis, and broad spectrum antiviral activity of 1-.beta.-D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides. J Med Chem [Internet]. 1972 Nov 1;15(11):1150–4. Available from: .
  8. 8. Stewart KD, Loren S, Frey L, Otis E, Klinghofer V, Hulkower KI. Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry. Bioorg Med Chem Lett [Internet]. 1998 Mar 3;8(5):529–34. Available from: .

Details

Primary Language

English

Subjects

Organic Chemical Synthesis, Organic Green Chemistry

Journal Section

Review

Publication Date

December 3, 2024

Submission Date

February 16, 2024

Acceptance Date

September 8, 2024

Published in Issue

Year 2024 Volume: 11 Number: 4

APA
Shekh Khdir, J. A., Aziz, D., Qader, I., Meena, B. I. M., & İbrahim, B. M. (2024). Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications. Journal of the Turkish Chemical Society Section A: Chemistry, 11(4), 1495-1514. https://doi.org/10.18596/jotcsa.1436801
AMA
1.Shekh Khdir JA, Aziz D, Qader I, Meena BIM, İbrahim BM. Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications. JOTCSA. 2024;11(4):1495-1514. doi:10.18596/jotcsa.1436801
Chicago
Shekh Khdir, Jwankar Abdulla, Dara Aziz, Ibrahim Qader, Bashdar Ismael Meena Meena, and Bnar Mahmoud İbrahim. 2024. “Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications”. Journal of the Turkish Chemical Society Section A: Chemistry 11 (4): 1495-1514. https://doi.org/10.18596/jotcsa.1436801.
EndNote
Shekh Khdir JA, Aziz D, Qader I, Meena BIM, İbrahim BM (December 1, 2024) Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications. Journal of the Turkish Chemical Society Section A: Chemistry 11 4 1495–1514.
IEEE
[1]J. A. Shekh Khdir, D. Aziz, I. Qader, B. I. M. Meena, and B. M. İbrahim, “Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications”, JOTCSA, vol. 11, no. 4, pp. 1495–1514, Dec. 2024, doi: 10.18596/jotcsa.1436801.
ISNAD
Shekh Khdir, Jwankar Abdulla - Aziz, Dara - Qader, Ibrahim - Meena, Bashdar Ismael Meena - İbrahim, Bnar Mahmoud. “Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications”. Journal of the Turkish Chemical Society Section A: Chemistry 11/4 (December 1, 2024): 1495-1514. https://doi.org/10.18596/jotcsa.1436801.
JAMA
1.Shekh Khdir JA, Aziz D, Qader I, Meena BIM, İbrahim BM. Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications. JOTCSA. 2024;11:1495–1514.
MLA
Shekh Khdir, Jwankar Abdulla, et al. “Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications”. Journal of the Turkish Chemical Society Section A: Chemistry, vol. 11, no. 4, Dec. 2024, pp. 1495-14, doi:10.18596/jotcsa.1436801.
Vancouver
1.Jwankar Abdulla Shekh Khdir, Dara Aziz, Ibrahim Qader, Bashdar Ismael Meena Meena, Bnar Mahmoud İbrahim. Nano-Catalytic Synthesis of 5-Substituted 1H Tetrazole Derivatives and Biological Applications. JOTCSA. 2024 Dec. 1;11(4):1495-514. doi:10.18596/jotcsa.1436801