Synthesis of Guanidines via Reaction of Amines with Carbodiimides in the Presence of Ionic Liquid

Year 2016, Volume: 3 Issue: 1, 19 - 26, 11.01.2016

Foad Shaghayeghi Toosi

Abstract

Different ionic liquids (ILs) were synthesized and evaluated for the preparation of substituted guanidines from the reaction of amines and carbodiimides. 1-methylimidazolium tetrafluoroborate [HMIm]BF4 was found to be the best ionic liquid for this reaction. This IL acted as a promoter for the addition of primary and secondary amines to carbodiimides. By this efficient approach, various guanidines were prepared in excellent yields.

Keywords

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References

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