Chemical reactivity of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl)-2,4-dioxobutanoate towards some nucleophilic reagents

Abstract

Abstract

A novel series of heterocyclic systems linked with quinolin-2-one was efficiently synthesized from reaction of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl) -2,4-dioxobutanoate (1) with a variety of nitrogen and/or carbon nucleophiles. A variety of heterocyclic systems such as pyrazoles, pyrimidines, pyrazines, oxazines and triazines containing quinoline moiety were synthesized. Structures of the new synthesized products were deduced on basis of their analytical and spectral data.

References

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