In vitro adsorption of metamizole sodium by activated carbon was studied
at pH 1.2 and 7.5 in order to simulate gastric and intestinal fluids. In the
first 5 minutes, more than eighty percent of the total adsorption occurred but
the adsorption process achieved to the equilibrium in 1 hour. Time to reach
equilibrium was not changed with the changing pH, concentration of the adsorbate
or the adsorbent amount. The equilibrium data followed the Langmuir model and therefore
fitted to L-type in accordance with the Giles classification for adsorption isotherms.
The maximum removal capacities of the activated carbon for metamizole sodium
were calculated using Langmuir equation and found as 185.19 mg/g and 161.29
mg/g at pH 1.2 and 7.5, respectively.
Adsorption Metamizole sodium Gastric fluid Intestinal fluid Dipyrone
Konular | Mühendislik, Kimya Mühendisliği |
---|---|
Bölüm | Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 1 Eylül 2017 |
Gönderilme Tarihi | 15 Kasım 2017 |
Kabul Tarihi | 24 Aralık 2017 |
Yayımlandığı Sayı | Yıl 2018 |