Constituents of Tanacetum Abratonifolium

Abstract

In this paper, terpenic metabolites of Tanacetum abratonifolium are reported. Eight known sesquiterpene lactones: tanachin (1), tavulin (2),  tamirin (3), spiciformin (4),  isospiciformin (5), 1β-hydroxy-6α-angeloxy-oxygermacra-4(5),10(14),11(13)-trien-8,12-olide (6), dentatin A (7), 1-β-hydroxy-6α-angeloyloxyeudesm-4(15), 11(13)-dien-8,12-olide (8) as well as  α-amyrin (9) and β-sitosterol (10) were isolated from the aerial parts of Tanacetum abratonifolium, collected in East Turkey.

Keywords

• Tanacetum abratonifolium,Asteraceae,Compositae,sesquiterpene lactones

References

1. 1. Davis PH, editor. Flora of Turkey and the East Aegean Islands. Edinburgh University Press, Edinburg. 1975; vol.5, 256-292.
2. 2. Duke JA, editor. CRC Handbook of Medicinal Herbs. CRC Press; 1987; 474-5
3. 3. Abad MJ, Bermejo P, Villar A. An approach to the genus Tanacetum L. (Compositae): phytochemical and pharmacological review. Phytotherapy Research. 1995; 9, 79-92
4. 4. Davis PH, Mill RR, Tan K. editor. Floro of Turkey and the East Aegean Islands (supplement). University Press, Edinburg. 1998.
5. 5. Yunusov AI, Kasymov ShZ, Sidyakin GP. Lactones of Tanacetum pseudoachillea. Khim. Prir. Soedin. 1973; 9, 276-277.
6. 6. Nano GM, Appendino G, Bicchi C, Frattini C. Wild Piedmontese plants. Part III. On a chemotype of Tanacetum vulgare L., containing sesquiterpene lactones with germacrane skeleton. Fitoterapia. 1980; 51(3), 135-140.
7. 7. Mnatsakanyan VA, Revazova LV. Phytochemical analysis of the plant Tanacetum myriophyllum. I. Sesquiterpenic lactones. Tamirin. Arm. Khim. Zh. 1973; 26(11), 914-919.
8. 8. Goren N, Arda N, Calıskan Z. Chemical characterization and biological activities of the genus Tanacetum. In: Atta-ur-Rahman (Ed.), Studies in Natural Products Chemistry, (Bioactive Natural Products, Part H), vol. 27. Elsevier, NewYork, Amsterdam, Losan, Singapor, Tokyo, 2002; 547–658.

9. 9. Goren N, Bozok-Johansson C, Jakupovic J, Lin L-J, Shieh HL, Cordell GA, Çelik N. Sesquiterpene lactones with antibacterial activity from Tanacetum densum subsp. sivasicum. Phytochemistry. 1992; 31(1), 101-104.
10. 10. Goren N, Jakupovic J, Topal Ş. Sesquiterpene lactones with antibacterial activity from Tanacetum argyrophyllum var. argyrophyllum. Phytochemistry. 1990; 29(5), 1467-1469.
11. 11. Goren N, Tahtasakal E. Sesquiterpenoids from Tanacetum argenteum subsp. canum var. canum. Phytochemistry. 1997; 45(1), 107-109.
12. 12. Yunusov AI, Abduazimov BKh, SidyakinGP. Dentatin A from Tanacetum vulgare. Khim Prir. Soedin. 1980; 4, 573.
13. 13. Goren N, Tahtasakal E. Constituents of Tanacetum densum subsp. Eginense. Phytochemistry. 1994; 36(5), 1281-2.
14. 14. Goren N, Tahtasakal E, Pezzuto JM, Cordell GA, Schwarz B, Proksch P. Sesquiterpene lactones from Tanacetum argenteum. Phytochemistry. 1994; 36(2), 389-392.
15. 15. Goren N, Woerdenbag HJ, Bozok-Johansson C. Cytotoxic and Antibacterial Activities of Sesquiterpene Lactones Isolated from Tanacetum praeteritum subsp. praeteritum. Planta Medica. 1996; 62(5), 419-422