A Schiff Base Sensor Selective to Anions, Biological Activity and Spectral Studies

Abstract

In this study, synthesis, characterization, anion sensor properties, and DNA binding of a benzothiazole-based Schiff base 4-bromo-2-((6-methoxybenzo[d]thiazol-2-ylimino)methyl)phenol have been investigated. The structure of the Schiff base was revealed with elemental analysis and spectroscopic methods. The colorimetric and fluorescent anion sensor properties of the Schiff base in DMSO were investigated by adding an equivalent amount of anions. In this context, the solution containing Schiff base had a color change after the addition of F^-, CN^-, AcO^-, H₂PO₄^- and OH^- anions, while the color change was not observed with the addition of Br^-, I^-, SCN^-, ClO₄^- and HSO₄^- anions. The anion-binding power of the compound was found to be F^->OH^->AcO^->CN^->H₂PO₄^- using UV-Vis spectrophotometry, respectively. The antimicrobial activity of the compound was investigated against some microorganisms. The compound showed activity against bacteria and yeast. Schiff base showed a similar effect against both bacteria and yeast. Interactions between the compound and CT-DNA were studied with UV-Vis spectra. The UV-Vis

Keywords

• Schiff base,Spectroscopy,Anion Sensors,DNA-Binding

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