Novel probes for selective fluorometric sensing of Fe(II) and Fe(III) based on BODIPY dyes

Abstract

Two novel boron-dipyrromethene (BODIPY) based fluorescence turn-off sensors, which demonstrate high selectivity and sensitivity toward Fe²⁺ and Fe³⁺ ions have been reported. A simple and high yielded synthesis of fluorescent BODIPY derivatives with malonyl unit for sensitization have been described. This approach provides quick, high yielded and low-cost preparation of probes. The two sensors have been comprised of combination of one and two BODIPY fluorophore and a malonyl unit, substituted on meso position of BODIPYs. Synthesized BODIPY derivatives have been characterized via elemental analyses, mass spectrometry, ¹H and ¹³C spectroscopy and their photophyisical properties were investigated by UV- Vis absorption and fluorescence emission spectroscopy.  The synthesized sensors (2, 3) have been used as a fluorescent probe towards the selective and sensitive detection of biologically important Fe²⁺ and Fe³⁺ ions in tetrahydrofuran by fluorescence spectroscopy. The limit of detection (LOD) have been calculated to be for the BODIPY 2, 14.61 (Fe²⁺), 1.22 (Fe³⁺) and for BODIPY 3, 1.16 (Fe²⁺) and 1.06 (Fe³⁺).

Keywords

• Borondipyrromethenes,UV-Vis spectroscopy,fluorescence,chemosensor

References

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