Bioactivity of Phaeophytin a, α-Amyrin and lupeol from Brachystelma togoense Schltr

Abstract

Phaeophytin a, α-amyrin and lupeol isolated from Brachystelma togoense were screened against S. aureus, E. coli, S. pneumonia, S. typhi, and C. albicans using Ciprofloxacin and Terbinafine as standards.  The result showed that these phytochemicals displayed antimicrobial activity against the tested organisms with the zone of inhibition from 12 – 27 mm. The result of MIC showed that Phaeophytin a was most active against C. albicans (0.09 mg/ml). The MBC showed that phaeophytin a and lupeol were the most active against S. aureus, S. pneumonia and S. typhi (0.37 mg/ml). The result of MFC showed that phaeophytin a was most active against C. albicans (0.1875 mg/ml).  The activity of these phytoconstituents in B. togoense justified ethnomedicinal uses of the plant. 

Keywords

• Bioactivity,Phaeophytin a,α-amyrin and lupeol

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