Öz
Kaynakça
- 1. Dömling A. Recent developments in isocyanide based multicomponent reactions in applied chemistry. Chemical Reviews. 2006; 106: 17-89.
- 2. Zhu J, Bienayme H. Eds. Multicomponent Reactions, Wiley-VCH: Weinheim, 2005, 484 p.
- 3. Sunderhaus J.D, Martin S.F. Application of multicomponent reactions to the synthesis of diverse heterocyclic scaffolds. Chemistry-A European Journal. 2009; 15: 1300-08.
- 4. Dömling A, Ugi I. Multicomponent reactions with isocyanides. Angewandte Chemie International Edition. 2000; 39: 3168-3210.
- 5. Zhu J, Wang Q, Wang M. X, Eds.; Multicomponent Reactions in Organic Synthesis, Wiley-VCH: Weinheim, 2015, 521 p.
- 6. Crenshaw R. R, Luke G. M, Smirnoff P. Interferon inducing activities of derivatives of 1,3-dimethyl-4-(3-dimethylaminopropylamino)-1H-pyrazolo[3,4-b]quinoline and related compounds. J. Med. Chem. 1976; 19: 262-275.
- 7. Crenshaw R, Luke G. M, Smirnoff P. Canadian Patent 10, 32, 538; Chem. Abstr. 89 (1978) 179995r.
- 8. Huang S, Lin R, Yu Y, Lu Y, Connolly P.J, Chiu G, Li S, Emanuel S.L, Middleton S.A. Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor. Bioorg. Med. Chem. Lett. 2007; 17: 1243-45.
- 9. Saggar S.A, Sisko J.T, Tucker T.J, Tynebor R.M, Su D.S, Antony N.J. US 2007021442, 2007.
- 10. Zhang P, Pennell A.M.K, Wright J.J.K, Chen W, Leleti M. R, Li Y, Li L, Xu Y. WO 2007002293, 2007 [Chem. Abstr. 2007, 146, 121980].
CSA-Catalyzed Three-component Synthesis of Fused Polycyclic Pyrazolo[4,3-e]pyridines Under Ultrasonic Irradiation and Their Antioxidant Activity
Öz
New fused
pyrazolo[4,3-e]pyridines were obtained by multi-component reaction of
1,3-dimethyl-1H-pyrazol-5-amine or
3-phenyl-1H-pyrazol-5-amine, aromatic
aldehydes and indan-1,3-dione in the presence of camphor-10-sulfonic acid (CSA)
as an effective catalyst under ultrasound promoted conditions. The antioxidant
activity of the pyrazolopyridine compounds 4b, 5c, 5e, 7a, 7b and 7c were determined.
Anahtar Kelimeler
Pyrazolopyridines multi-component synthesis ultrasonic irradiation camphor-10-sulfonic acid (CSA)
Kaynakça
- 1. Dömling A. Recent developments in isocyanide based multicomponent reactions in applied chemistry. Chemical Reviews. 2006; 106: 17-89.
- 2. Zhu J, Bienayme H. Eds. Multicomponent Reactions, Wiley-VCH: Weinheim, 2005, 484 p.
- 3. Sunderhaus J.D, Martin S.F. Application of multicomponent reactions to the synthesis of diverse heterocyclic scaffolds. Chemistry-A European Journal. 2009; 15: 1300-08.
- 4. Dömling A, Ugi I. Multicomponent reactions with isocyanides. Angewandte Chemie International Edition. 2000; 39: 3168-3210.
- 5. Zhu J, Wang Q, Wang M. X, Eds.; Multicomponent Reactions in Organic Synthesis, Wiley-VCH: Weinheim, 2015, 521 p.
- 6. Crenshaw R. R, Luke G. M, Smirnoff P. Interferon inducing activities of derivatives of 1,3-dimethyl-4-(3-dimethylaminopropylamino)-1H-pyrazolo[3,4-b]quinoline and related compounds. J. Med. Chem. 1976; 19: 262-275.
- 7. Crenshaw R, Luke G. M, Smirnoff P. Canadian Patent 10, 32, 538; Chem. Abstr. 89 (1978) 179995r.
- 8. Huang S, Lin R, Yu Y, Lu Y, Connolly P.J, Chiu G, Li S, Emanuel S.L, Middleton S.A. Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor. Bioorg. Med. Chem. Lett. 2007; 17: 1243-45.
- 9. Saggar S.A, Sisko J.T, Tucker T.J, Tynebor R.M, Su D.S, Antony N.J. US 2007021442, 2007.
- 10. Zhang P, Pennell A.M.K, Wright J.J.K, Chen W, Leleti M. R, Li Y, Li L, Xu Y. WO 2007002293, 2007 [Chem. Abstr. 2007, 146, 121980].
Ayrıntılar
| Konular | Mühendislik, Kimya Mühendisliği |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 16 Mayıs 2017 |
| Gönderilme Tarihi | 2 Mart 2017 |
| Kabul Tarihi | 8 Mayıs 2017 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 4 Sayı: 2 |
Cited By
Synthesis, solar cell application, and biological study of vinyl substituted isophorone derivatives
Research on Chemical Intermediates
Zehra Kozak
https://doi.org/10.1007/s11164-019-03924-y
