Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents

Year 2018, Volume: 5 Issue: 1, 73 - 84, 01.09.2017

Omer Tahir Gunkara , Nuket Ocal

https://doi.org/10.18596/jotcsa.338218

Abstract

[3+2]-Cycloaddition
reactions of N-phthalimide substituted
tricyclic imide were studied to synthesize their isoxazoline and bispiro
derivatives in excellent yields. All new synthesized compounds have been
characterized by their FTIR, ¹H NMR, ¹³C NMR, GC/MS and
LC/MS (HRMS) analyses.

Keywords

Azomethine ylide, Bispiromolecules, Isoxazolines, Tetracyclic imides, (3+2)-Cycloaddition reaction

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