Adsorption Of Metamizole Sodium By Activated Carbon In Simulated Gastric And Intestinal Fluids

Yıl 2018, Cilt: 5 Sayı: 1, 237 - 246, 01.09.2017

Elif Caliskan Salihi

https://doi.org/10.18596/jotcsa.353590

Cited By: 5

Öz

In vitro adsorption of metamizole sodium by activated carbon was studied
at pH 1.2 and 7.5 in order to simulate gastric and intestinal fluids. In the
first 5 minutes, more than eighty percent of the total adsorption occurred but
the adsorption process achieved to the equilibrium in 1 hour. Time to reach
equilibrium was not changed with the changing pH, concentration of the adsorbate
or the adsorbent amount. The equilibrium data followed the Langmuir model and therefore
fitted to L-type in accordance with the Giles classification for adsorption isotherms.
The maximum removal capacities of the activated carbon for metamizole sodium
were calculated using Langmuir equation and found as 185.19 mg/g and 161.29
mg/g at pH 1.2 and 7.5, respectively.     

Anahtar Kelimeler

Adsorption, Metamizole sodium, Gastric fluid, Intestinal fluid, Dipyrone

Kaynakça

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