A Novel One-Pot Green Synthesis and Characterization of Substitue Bis-Iminothiazolidinones

Yıl 2018, Cilt: 5 Sayı: 3, 1061 - 1070, 01.09.2018

Fatma Tülay Tugcu

https://doi.org/10.18596/jotcsa.440080

Öz

In this study, some new 5-substituted bis-iminothiazolidinone derivatives have been synthesized via one-pot green synthesis. The study comprises two steps. In the first step, bis-thioureas were prepared by the reaction of aryl isothiocyanates with substituted amines. In the second step, substituted bis-thioureas prepared beforehand and chloroacetic acid were condensed with substituted thiophene-2-carboxaldehydes and new 5-substituted bis-iminothiazolidinone compounds were obtained. The structures of all these synthesized compounds were determined and characterized by infrared, nuclear magnetic resonance and mass spectral data.

Anahtar Kelimeler

bis-thiourea, 5-Substituted bis-iminothiazolidinone, one-pot reaction, green synthesis

Kaynakça

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