Yıl 2020, Cilt 1 , Sayı 1, Sayfalar 18 - 24 2020-04-01

An update on cyclodextrins as drug vehicles for antimicrobial applications

Ece ÖZCAN BÜLBÜL [1] , Kalliopi ELEFTHERIADOU [2] , Neslihan ÜSTÜNDAĞ OKUR [3] , Panoraia SİAFAKA [4]

Cyclodextrins belong to cyclic oligosaccharides comprised of α-(1,4) linked glucopyranose groups. Their interesting supramolecular cavity-like structure can host active molecules providing a breeding ground for drug delivery systems. Cyclodextrins, due to their unique functional structure, can produce host-guest complexes with active ingredients, such as drugs, peptides, proteins, etc.; the complexes resulted from intramolecular interactions leading to stable molecules vehicles. Moreover, cyclodextrins are already applied in pharmaceutical industry applications since they can induce the solubility of lipophilic compounds and provide bioavailability and excellent safety profile and stability. In this review, the basic background for cyclodextrins and their current applications in the antimicrobial field are discussed. Besides, the antibacterial and antifungal-applications in the pharmaceutical field attract most researchers because of microbes’ resistance. Regarding this, the most recent cyclodextrin inclusion complexes with antimicrobial and antifungal drugs are summarized in this article.
Antibacterial, Antifungal, Cyclodextrins, Inclusion Complexes, Solid Dispersions
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Birincil Dil en
Konular Farmakoloji ve Eczacılık
Bölüm Review Articles

Orcid: 0000-0001-7112-923X
Ülke: Turkey

Orcid: 0000-0003-3192-8269
Kurum: Aristotle University of Thessaloniki
Ülke: Greece

Orcid: 0000-0002-3210-3747
Yazar: Neslihan ÜSTÜNDAĞ OKUR (Sorumlu Yazar)
Kurum: University of Health Sciences, Faculty of Pharmacy
Ülke: Turkey

Orcid: 0000-0001-7256-3230
Yazar: Panoraia SİAFAKA
Kurum: Aristotle University of Thessaloniki
Ülke: Greece

Teşekkür None

Başvuru Tarihi : 16 Mayıs 2020
Kabul Tarihi : 29 Mayıs 2020
Yayımlanma Tarihi : 1 Nisan 2020

Bibtex @derleme { jpharmtech738520, journal = {Journal of Pharmaceutical Technology}, issn = {}, eissn = {2717-7904}, address = {Anadolu Üniversitesi Eczacılık Fakültesi Farmasötik Teknoloji Abd Tepebaşı Eskişehir}, publisher = {Mustafa Sinan KAYNAK}, year = {2020}, volume = {1}, pages = {18 - 24}, doi = {10.37662/jpt.2020.3}, title = {An update on cyclodextrins as drug vehicles for antimicrobial applications}, key = {cite}, author = {Özcan Bülbül, Ece and Eleftherıadou, Kalliopi and Üstündağ Okur, Neslihan and Si̇afaka, Panoraia} }
APA Özcan Bülbül, E , Eleftherıadou, K , Üstündağ Okur, N , Si̇afaka, P . (2020). An update on cyclodextrins as drug vehicles for antimicrobial applications . Journal of Pharmaceutical Technology , 1 (1) , 18-24 . DOI: 10.37662/jpt.2020.3
MLA Özcan Bülbül, E , Eleftherıadou, K , Üstündağ Okur, N , Si̇afaka, P . "An update on cyclodextrins as drug vehicles for antimicrobial applications" . Journal of Pharmaceutical Technology 1 (2020 ): 18-24 <https://dergipark.org.tr/tr/pub/jpharmtech/issue/54396/738520>
Chicago Özcan Bülbül, E , Eleftherıadou, K , Üstündağ Okur, N , Si̇afaka, P . "An update on cyclodextrins as drug vehicles for antimicrobial applications". Journal of Pharmaceutical Technology 1 (2020 ): 18-24
RIS TY - JOUR T1 - An update on cyclodextrins as drug vehicles for antimicrobial applications AU - Ece Özcan Bülbül , Kalliopi Eleftherıadou , Neslihan Üstündağ Okur , Panoraia Si̇afaka Y1 - 2020 PY - 2020 N1 - doi: 10.37662/jpt.2020.3 DO - 10.37662/jpt.2020.3 T2 - Journal of Pharmaceutical Technology JF - Journal JO - JOR SP - 18 EP - 24 VL - 1 IS - 1 SN - -2717-7904 M3 - doi: 10.37662/jpt.2020.3 UR - https://doi.org/10.37662/jpt.2020.3 Y2 - 2020 ER -
EndNote %0 Journal of Pharmaceutical Technology An update on cyclodextrins as drug vehicles for antimicrobial applications %A Ece Özcan Bülbül , Kalliopi Eleftherıadou , Neslihan Üstündağ Okur , Panoraia Si̇afaka %T An update on cyclodextrins as drug vehicles for antimicrobial applications %D 2020 %J Journal of Pharmaceutical Technology %P -2717-7904 %V 1 %N 1 %R doi: 10.37662/jpt.2020.3 %U 10.37662/jpt.2020.3
ISNAD Özcan Bülbül, Ece , Eleftherıadou, Kalliopi , Üstündağ Okur, Neslihan , Si̇afaka, Panoraia . "An update on cyclodextrins as drug vehicles for antimicrobial applications". Journal of Pharmaceutical Technology 1 / 1 (Nisan 2020): 18-24 . https://doi.org/10.37662/jpt.2020.3
AMA Özcan Bülbül E , Eleftherıadou K , Üstündağ Okur N , Si̇afaka P . An update on cyclodextrins as drug vehicles for antimicrobial applications. J Pharm Technol. 2020; 1(1): 18-24.
Vancouver Özcan Bülbül E , Eleftherıadou K , Üstündağ Okur N , Si̇afaka P . An update on cyclodextrins as drug vehicles for antimicrobial applications. Journal of Pharmaceutical Technology. 2020; 1(1): 18-24.