Yıl 2020, Cilt 1 , Sayı 1, Sayfalar 13 - 17 2020-04-01

Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction

Gülşah GEDİK [1] , Seda ALACA [2]


This is a study of the brown algae-derived hydrolyzed algin as used in eye cream formulation. Alginic acid sodium is a gelling and non-toxic anionic polysaccharide, which is used to bone tissue engineering, preparation of alginate hydrogels, encapsulating, hydrating, protective, and de-polluting action. The skin of eye contour is thinner and less dense in support fibres than other parts of the face. Therefore, cutaneous sagging is frequently seen to appear around 40 years of age, very often aggravated by environmental factors such as pollution. The objective of the study was to evaluate the effect of anti-pollution & anti-aging eye cream on the collagen contraction. The outcomes of the characterization analysis indicate the development of successful cream formulation with optimum characteristics. No microbial growth was observed. The collagen lattices were prepared with human dermal fibroblasts, for evaluation of the effect of the cream on the collagen contraction. The lattices were treated or not (control) with the tested cream and then incubated at 37°C for 96 hours. The surface of lattices was measured by image analysis, and the lattices contraction was analyzed at 16, 24, 40, 48, 64, 72, 88, and 96 hours (the measure of lattices area). The treatment with eye cream at 0.5% decreases the surface of the lattice compared to the control (no treatment). According to the results obtained under the conditions of the test, the eye cream tends to increase the collagen contraction and a significative decrease of the lattice surface by 6.68% compared to the control at 16 hours.
Anti-Aging, Anti-Pollution, Collagen, Collagen Contraction, Eye Cream
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Birincil Dil en
Konular Farmakoloji ve Eczacılık
Bölüm Research Articles
Yazarlar

Orcid: 0000-0003-4147-6729
Yazar: Gülşah GEDİK (Sorumlu Yazar)
Kurum: TRAKYA UNIVERSITY
Ülke: Turkey


Orcid: 0000-0002-9433-7055
Yazar: Seda ALACA
Kurum: Tan- Alize Kozmetik A.Ş.
Ülke: Turkey


Tarihler

Başvuru Tarihi : 24 Mayıs 2020
Kabul Tarihi : 31 Mayıs 2020
Yayımlanma Tarihi : 1 Nisan 2020

Bibtex @araştırma makalesi { jpharmtech742240, journal = {Journal of Pharmaceutical Technology}, issn = {}, eissn = {2717-7904}, address = {Anadolu Üniversitesi Eczacılık Fakültesi Farmasötik Teknoloji Abd Tepebaşı Eskişehir}, publisher = {Mustafa Sinan KAYNAK}, year = {2020}, volume = {1}, pages = {13 - 17}, doi = {10.37662/jpt.2020.2}, title = {Evaluation of the effect of anti-pollution \& anti-aging eye cream on the collagen contraction}, key = {cite}, author = {Gedi̇k, Gülşah and Alaca, Seda} }
APA Gedi̇k, G , Alaca, S . (2020). Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction . Journal of Pharmaceutical Technology , 1 (1) , 13-17 . DOI: 10.37662/jpt.2020.2
MLA Gedi̇k, G , Alaca, S . "Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction" . Journal of Pharmaceutical Technology 1 (2020 ): 13-17 <https://dergipark.org.tr/tr/pub/jpharmtech/issue/54396/742240>
Chicago Gedi̇k, G , Alaca, S . "Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction". Journal of Pharmaceutical Technology 1 (2020 ): 13-17
RIS TY - JOUR T1 - Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction AU - Gülşah Gedi̇k , Seda Alaca Y1 - 2020 PY - 2020 N1 - doi: 10.37662/jpt.2020.2 DO - 10.37662/jpt.2020.2 T2 - Journal of Pharmaceutical Technology JF - Journal JO - JOR SP - 13 EP - 17 VL - 1 IS - 1 SN - -2717-7904 M3 - doi: 10.37662/jpt.2020.2 UR - https://doi.org/10.37662/jpt.2020.2 Y2 - 2020 ER -
EndNote %0 Journal of Pharmaceutical Technology Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction %A Gülşah Gedi̇k , Seda Alaca %T Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction %D 2020 %J Journal of Pharmaceutical Technology %P -2717-7904 %V 1 %N 1 %R doi: 10.37662/jpt.2020.2 %U 10.37662/jpt.2020.2
ISNAD Gedi̇k, Gülşah , Alaca, Seda . "Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction". Journal of Pharmaceutical Technology 1 / 1 (Nisan 2020): 13-17 . https://doi.org/10.37662/jpt.2020.2
AMA Gedi̇k G , Alaca S . Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction. J Pharm Technol. 2020; 1(1): 13-17.
Vancouver Gedi̇k G , Alaca S . Evaluation of the effect of anti-pollution & anti-aging eye cream on the collagen contraction. Journal of Pharmaceutical Technology. 2020; 1(1): 13-17.